BACKGROUND Treatments for patients with chronic idiopathic urticaria (CIU)chronic spontaneous urticaria (CSU) who were unresponsive to antihistamines include oral corticosteroids (OCS). Risks of OCS-related side effects in these patients have not been described quantitatively. OBJECTIVE To investigate the relationship between OCS use and the risk of developing side effects possibly attributab...

BACKGROUND The current EAACI/GA2LEN/EDF/WAO guideline for urticaria provide specific recommendations for the diagnostic workup and treatment of patients with chronic spontaneous urticaria (CsU). This study explored if physicians in Ecuador know these recommendations and implement them in their actual clinical practice for CsU. METHODS We investigated physicians who treat CsU patients in a cro...

Histamine is a critical mediator if itch in urticaria, however, many patients with chronic spontaneous urticaria (CSU) spite of treatment antihistamines. Further, it widely known that the CSU, over time can lose clinical responses to antihistamines as well. We hypothesized limitation these therapies partially due other immune mediators amplifying histaminergic pathway. focused specifically on I...

Background: Chronic urticaria (CU) is characterized as the recurrent occurrence of wheals, angioedema, or both on most days week, for more than six weeks. Information available this disease mainly based foreign studies. We observed clinical characteristics among our population to fill shortage information. Materials and Methods: It was a hospital-based, cross-sectional, descriptive study conduc...

Background: Autologous serum (ASST) and plasma (APST) skin testing confirm autoreactivity in chronic spontaneous urticaria (CSU). Whole blood autohemotherapy has been used. Plasma even whole may be used instead of with relatively quicker preparation cheaper method especially using the latter centers limited resources. Purpose: The purpose study is to determine if similar intradermal reactions c...

BACKGROUND Chronic spontaneous urticaria (CSU) is a common skin disorder with etiology that is not well understood. METHODS In this study, we evaluated the prevalence of autologous serum skin test (ASST) and skin prick testing (SPT) to house dust mite (HDM) in 862 CSU cases in China. Clinical features, courses and treatment responses were also recorded. RESULTS The prevalence of positive AS...

Mục tiêu: Khảo sát đặc điểm lâm sàng, cận sàng bệnh mày đay mạn tính cảm ứng (chronic inducible urticaria-CIndU). Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang dựa trên dữ liệu của 142 nhân được chẩn đoán xác định CIndU, tới khám tại viện Da liễu Trung Ương từ tháng 07/2021 07/2022. Kết quả: Trong các thể CindU, chứng da vẽ nổi là phổ biến nhất, chiếm 46,5%, do choline đứng th...

Chronic spontaneous urticaria (CSU) is a highly debilitating skin disease associated with systemic features. We have made significant progress in several aspects relating to this condition. However, the exact physiopathology remains unknown. There is mounting evidence for an autoimmune basis, demonstrated by the CSU serum ability to activate healthy donors skin mast cells and blood basophils. H...

BACKGROUND Omalizumab is approved in the UK as add-on treatment for chronic spontaneous urticaria (CSU) in patients with inadequate response to H1-antihistamines. Ciclosporin is an established but unlicensed 3rd line option for CSU. Two parallel retrospective observational studies were conducted to describe outcomes of treatment and adverse events with omalizumab or ciclosporin for CSU treatmen...

Interferon- (IFN-) λ1 is regarded as a potent bio-active molecule in innate immunity. However, little is known about its role in chronic spontaneous urticaria (CSU). We therefore investigated expression of IFN-λ1 in CSU, its cellular location, and its influence on inflammatory cell accumulation by using flow cytometry analysis, skin tissue dispersion, immunohistochemical stain, and a mouse peri...