BACKGROUND Duplex real-time PCR assays have been widely used to determine amounts and concentrations of free circulating DNA in human blood plasma samples. Circulatory plasma DNA is highly fragmented and hence a PCR-based determination of DNA concentration may be affected by the limited availability of full-length targets in the DNA sample. This leads to inaccuracies when counting PCR target co...

Mortality from avoidable circulatory system diseases causes one of the major losses in life expectancy, especially males and population working ages. The main contributors are deaths caused by ischaemic heart diseases, cerebrovascular hypertensive diseases. This article analyses trends mortality estimates possible increases expectancy due to elimination these death. In this regard, author uses ...

In this work a pneumatically driven mock left ventricle and a native left ventricle are modeled and alternatively connected to the numerical model of a closed circulatory system comprising the systemic circulation, the left atrium, and inlet and outlet ventricular valves. By simulating physiological changes of the system working conditions, behavior and preload sensitivity of the pneumatic vent...