Platinosis (severe dermatitis and/or asthma) may be broadly defined as the effects of soluble platinum salts on people exposed to them occupationally. Platinum coordination complexes are widely used in the treatment of a variety of solid tumors. However, the clinical use of cisplatin (the most useful agent) is limited by the development of nephrotoxicity. High dose exposure of soluble platinum ...

Horse spleen ferritin was found to bind aluminium poorly after equilibrium dialysis with buffered aluminium citrate solutions. Not more than 10 aluminium atoms/ferritin molecule were bound from a 25 microM-aluminium solution, pH 7.4, and the degree of binding was dependent on the method used to prepare the aluminium citrate solution. Up to 120 aluminium atoms/molecule were bound when ferritin i...

Enterotube, a multiple-test system which combines nine biochemical tests useful in the identification of members of the family Enterobacteriaceae, was tested and compared with the PathoTec test system in the identification of gram-negative bacilli isolated from clinical specimens. It was found that both the Enterotube and the PathoTec systems rapidly and accurately defined the position of the o...

background: clomiphene citrate (cc) an agonist and antagonist of estrogen, is the first line treatment in ovarian stimulation. anti-estrogenic effect of cc in endometrial thickness and cervical mucus has negative effect on pregnancy rate. letrozole is an aromatase inhibitor has been seen that has acceptable pregnancy rate compared to cc. objective: the aim of this study was to compare the effic...

in the present work, magnetic nanocomposites of the multi-walled carbon nanotubes (mwcnts) decorated with magnesium ferrite (mgfe2o4) nanoparticles were synthesized successfully by citrate-gel method. the shape, structure, size, and properties of the as-synthesized sample were characterized by fourier transform infrared spectroscopy (ftir), x-ray diffraction pattern (xrd), transmission electron...

this study was designed to compare the effect of clomiphene and letrozole in ovulatory stimulation in infertile women under intrauterine insemination who referred to mahdiyeh infertility clinic during 2008-2009. 106 infertile women were randomly divided into two equal groups. patients were treated with 5 mg of letrozole daily (in letrozole group) or 100 mg of clomiphene citrate daily (in clomip...

Abstract Blood coagulation is a process, which initiated by certain physico-chemical effects. This process results in change the blood from sol state, that well suited for further processing, to gel state. 13 clotting factors take part cascade system of coagulation. Trisodium-citrate affects factor IV, calcium, and prevents texture. The effect different concentrations trisodium-citrate (0, 0.48...

Recent advances in the use of gold nanoparticles (Au NPs)/antibody conjugations nanomedicine have increased need to optimize synthesis conditions and surface functionalization Au NPs. In this study, a home-made Neisseria meningitidis recombinant antibody (scFv-Fc) was developed by connecting fragment crystallizable (Fc) region human with mouse (single-chain variable (scFv)) characterized using ...

Normal prostate tissue contains high levels of citrate. In the presence of prostate cancer, the citrate level is diminished. In this paper we show that it is possible to use europium-oxytetracycline complex as a citrate fluorescent probe and consequently as a prostate cancer probe. We analyzed normal nude male mice urine and urine from nude male mice in which prostate cancer was induced by intr...

we report herein the development of a highly sensitive colorimetric method for the detection of 4-hydroxy-2-mercapto-6-methylpyrimidine (mtu) which acts as an anti-thyroid drug utilizing citrate capped gold nanoparticles (au-nps). this thiol-containing molecule exhibits intriguing affinity with au-nps. the reactivity involves the displacement of the citrate shell by the thiolate shell followed ...