Multiple myeloma is a slowly proliferating disease of ‘mature B cells’, involving mainly the bone marrow. Active myeloma is often preceded by an indolent phase of monoclonal gammopathy of undetermined significance or smoldering myeloma. Although patients at this stage do not require therapy, genetically, the plasma cells are already very abnormal with the large majority of such patients having ...

Penelitian ini dilatarbelakangi oleh beberapa hal yang di temukan peneliti kreativitas anak kurang berkembang dengan baik serta kurangnya fasilitas dan metode pembelajaran dalam mengembangkan kreativitas. bertujuan untuk melihat pengaruh kreasi kulit jagung terhadap pengembangan usia 5-6 tahun. Jenis penelitian adalah kuantitatif eksperimen menggunakan clasical eksperimental design, acuan clust...

Thomas Fogle is Associate Professor and Chair of the Department of Biology at Saint Mary's College. He received his B.A. in Biology from Thiel College, M.A. in Zoology from Southern Illinois University at Carbondale, and Ph.D. in Genetics from North Carolina State University. He teaches introductory biology, genetics, and human genetics. His research interests include human cytogenetics, the cy...

The 'Atlas of Genetics and Cytogenetics in Oncology and Haematology' (http://www.infobiogen.fr/services/chromcancer) contains concise and updated cards on genes involved in cancer, cytogenetics and clinical entities in oncology, and cancer-prone diseases, a portal towards genetics/cancer, and teaching materials in genetics. This database is made for and by researchers and clinicians, who are en...

A 5 day old male with bilateral anophthalmos, hypospadias, bifid scrotum, micrognathia, and cleft palate with normal chromosomes is described. There have been two case reports with similar clinical manifestations but associated with interstitial deletion of 14q (q22q23). We propose that either our patient represents a new syndrome or has a microdeletion which could not be detected on routine cy...

Chromosomal microarray technology represents the technical convergence of molecular genetics and cytogenetics, and is rapidly revolutionizing modern cytogenetics. Expected genomic aberrations are accurately identified and provide readily interpretable results that are suitable for clinical risk stratification and therapeutic strategies. The applic...