Ultrasonographic examination is widely used for screening of abnormal findings on prenatal screening. Cleft lip with or without cleft palate of the fetus can also be screened by using ultrasonography. Presence of abnormal findings of the fetal lip or palate can be detected by the imaging professionals. However, such findings may not be familiar to oral and maxillofacial surgeons. Oral and maxil...

To determine quality of life of parents of children with cleft lip and palate and to compare it with parents of non cleft lip and palate children. World Health Organisation Quality of Life (Bref, Field Trial version,1996) for parents of children with cleft lip and palate. Total of 40 parents were questioned , 20 were parents of CLP children and the other 20 were parents of non cleft children. T...

Objective(s:Cleft lip/palate are common congenital anomalies, affecting approximately 2/1000 live births. Pierre Robin Sequence is a subgroup of the cleft palate population. Chromosomal abnormalities near the SOX9 gene disrupt the regulation of this gene and prevent the SOX9 protein from properly controlling the development of facial structures, which leads to isolated PRS. The present study wa...

Patients with cleft lip and palate usually present dental anomalies of number, shape, structure and position in the cleft area and the general dentist is frequently asked to restore or extract those teeth. Considering that several anatomic variations are expected in teeth adjacent to cleft areas and that knowledge of these variations by general dentists is required for optimal treatment, the ob...

introduction: orofacial clefts are among the most common congenital anomalies. patients presenting with orofacial clefts often require surgery or other complex procedures. a cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. the reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnost...

OBJECTIVES The authors performed a systematic review and meta-analysis to investigate the possible correlation between ambient air pollution and orofacial cleft anomalies in newborns. MATERIAL AND METHODS A literature search was performed using the PubMed and Google Scholar, using the keywords "air pollution", "cleft lip", "cleft palate", "carbon monoxide", "ozone", "sulfur dioxide", "nitroge...

The AEC syndrome or Hay wells is an unusual autosomal dominant disorder characterised by Ankyloblepharon, Ectodermal dysplasia and Cleft palate and/or lip. This occurs as a result of missense mutation in TP63 affecting P63 SAM the gene, which protein-protein interaction domain. It associated with some irregularities like /Cleft lip, severe scalp erosions abnormalities epidermal appendages inclu...

BACKGROUND Alveolar and nasal reconstruction for patients with cleft lip and palate is a challenge for the reconstructive surgeon. Various procedures have been attempted to reduce the cleft gap so as to obtain esthetic results post surgically. Yet there is need of continuous exploration of newer and better methods. Rehabilitation of cleft lip and palate generally requires a team approach with p...

The presence of a cleft lip, cleft palate or both, has a huge impact on the life of an individual and their family. Modern management has much to offer these people, revolutionizing appearance and functional defects to a point where they may be difficult to detect. Surgery aims to correct the anatomically obvious cleft lip, augment normal dento-alveolar development and lead to effective palatal...