نتایج جستجو برای: clinically isolated syndrome

تعداد نتایج: 1033495  

Journal: :Journal of neurology, neurosurgery, and psychiatry 2001
P A Brex K A Miszkiel J I O'Riordan G T Plant I F Moseley A J Thompson D H Miller

OBJECTIVES With increasing evidence that permanent tissue damage occurs early in the course of multiple sclerosis, it is important that treatment trials include patients in the earliest stages of the disease. For many patients with multiple sclerosis the first presentation is a clinically isolated syndrome. Not all patients with a clinically isolated syndrome develop multiple sclerosis, however...

Journal: :The New England journal of medicine 2003
Thomas Berger Paul Rubner Franz Schautzer Robert Egg Hanno Ulmer Irmgard Mayringer Erika Dilitz Florian Deisenhammer Markus Reindl

BACKGROUND Most patients with multiple sclerosis initially present with a clinically isolated syndrome. Despite the fact that clinically definite multiple sclerosis will develop in up to 80 percent of these patients, the course of the disease is unpredictable at its onset and requires long-term observation or repeated magnetic resonance imaging (MRI). We investigated whether the presence of ser...

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