OBJECTIVE To determine the day of ovulation by the salivary ferning test in clomiphene citrate-treated women. DESIGN A descriptive study. SETTING Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. SUBJECT Seventy-five infertile women with regular menstrual cycles. MATERIAL AND METHOD Infertile women were given 100 mg of clomiphene ...

BACKGROUND Artificial insemination (intrauterine insemination by husband or artificial insemination by husband) is often tried as first treatment for couples with unexplained infertility. Pertubation has previously proved to increase the chance of achieving pregnancy for these couples. The effect of pertubation on fertility can be mechanical as well as anti-inflammatory by using a substance tha...

BACKGROUND Unovulation is the most common cause of infertility. The first line oral treatment has been clomiphene citrate. Another anti-estrogen used for ovulation induction is tamoxifen. Many unovulatory infertile women are resistance to anti-estrogens and need another treatment. Alternative treatments are aromatas inhibitors. OBJECTIVE This study was designed to compare the effectiveness of...

Background: Clomiphene citrate (CC) is still holding its place as the first-line treatment for induction of ovulation in polycystic ovary syndrome (PCOS) patients.  Objective: to assess effect extended clomiphene on pregnancy outcomes resistant PCOS. Patients and methods: this study was conducted 48 PCO patients with CC resistance attended Obstetrics Gynecology Outpatient Clinic at Menoufia U...

Body has defense mechanisms against oxidants in the form of both enzymatic and non enzymatic antioxidants. Oxidants have both physiological and pathological role in female reproduction. Oxidative stress causes damage to the ovaries, oogonia and ovulation as well as in implantation procedures. A study was undertaken to evaluate the polycystic ovary syndrome (PCOS) induced stress in ovarian and u...

OBJECTIVE To evaluate the impact of luteal phase support with vaginal progesterone on pregnancy rates in the intrauterine insemination (IUI) cycles, stimulated with clomiphene citrate and human menopausal gonadotropin (hMG), in sub fertile couples. MATERIALS AND METHODS This prospective, randomized, double blind study was performed in a tertiary infertility center from March 2011 to January 2...

BACKGROUND N-acetyl cysteine (NAC) was proposed as an adjuvant to clomiphene citrate for ovulation induction in patients with polycystic ovary syndrome (PCOS) without clomiphene citrate resistance. OBJECTIVE To evaluate the effect of NAC on pregnancy rate in PCOS patients who were candidates for intrauterine insemination. MATERIALS AND METHODS In this randomized clinical trial, 97 PCOS wome...

A total of 811 intrauterine insemination (IUI) cycles in which clomiphene citrate/human menopausal gonadotrophin (HMG) was used for ovarian stimulation were analysed retrospectively to identify prognostic factors regarding treatment outcome. The overall pregnancy rate was 12.6% per cycle, the multiple pregnancy rate 13.7%, and the miscarriage rate 23.5%. Logistic regression analysis revealed fi...