نتایج جستجو برای: clonal selection
تعداد نتایج: 340218 فیلتر نتایج به سال:
In this paper, a method based on clonal selection algorithm (CLONALG) is proposed for null steering of linear antenna arrays by controlling only the positions of selected elements. The CLONALG is a relatively novel population-based evolutionary algorithm inspired by the clonal selection principle of the human immune system. In order to illustrate the accuracy and flexibility of the proposed alg...
Life history evolution of many clonal plants takes place with long periods of exclusively clonal reproduction and under largely varying ramet densities resulting from clonal reproduction. We asked whether life history traits of the clonal herb Ranunculus reptans respond to density-dependent selection, and whether plasticity in these traits is adaptive. After four generations of exclusively clon...
Cytokines that use the common receptor gamma-chain for regulating CD8(+) T cell responses to Ag include IL-2, IL-15, and the recently identified IL-21. The ability of these cytokines to regulate antitumor activity in mice has generated considerable interest in understanding their mode of action. In this study we compare the abilities of IL-2, IL-15, and IL-21 to stimulate immunity against tumor...
The costimulatory receptor OX40 has recently been shown to be involved in primary CD4 responses to several defined Ags. However, to date there has been little information regarding the mechanism of action of OX40, such as whether it regulates T cell numbers, reactivity, or both, and whether it contributes to induction of long-term T cell responses. With an agonist Ab to OX40, and by tracking Ag...
Abstract Clonal evolution, the process of expansion and diversification mutated cells, plays an important role in cancer development, resistance, relapse. Although clonal evolution is most often conceived as driven by natural selection, recent studies uncovered that neutral shapes a significant proportion solid cancers. In hematological malignancies, interplay between selection also disputed. B...
Clonal selection was a natural choice mode of immune system, in which the antibody with high affinity for antigen was promoted and the antibody with low affinity was restrained under the action of clonal selection mechanism. And Clonal Selection Algorithm (CSA) as one kind of searching methods adopted group search strategy, exchanged information between antibodies and achieved global optimal so...
Clonal culture is crucial for experimental protocols that require growth or selection of pure populations of cells. Currently, there is no method for deriving neural stem cells (NSCs) clonally from single human embryonic stem cells (hESCs). Bulk derivation of neural progenitors from hESCs for cell therapies can lead to a host of problems including incomplete differentiation leading to prolifera...
Both the clonal selection algorithm (CSA) and the ant colony optimization (ACO) are inspired by natural phenomena and are effective tools for solving complex problems. CSA can exploit and explore the solution space parallely and effectively. However, it can not use enough environment feedback information and thus has to do a large redundancy repeat during search. On the other hand, ACO is based...
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