The mannose-binding agglutinin from bulbs of Lycoris aurea (LAA) agglutinates rabbit but not human erythrocytes. The molecular mass of the monomer in SDS/PAGE is 12 kDa while the apparent molecular mass in gel filtration is 48 kDa, indicating that LAA is a homotetramer. The full-length cDNA of LAA contains 683 bp with an open reading frame encoding a protomer of 162 amino-acid residues. Hydroph...

Influenza has been circulating in the human population and has caused three pandemics in the last century (1918 H1N1, 1957 H2N2 and 1968 H3N2). The 2009 A(H1N1) was classified by World Health Organization as the fourth pandemic. Influenza has a high evolution rate, which makes vaccine design challenging. We here consider an approach for early detection of new dominant strains. By clustering the...

We describe the implementation and performance of the P3T (Particle-Particle Particle-Tree) scheme for simulating dense stellar systems. In P3T, the force experienced by a particle is split into short-range and long-range contributions. Short-range forces are evaluated by direct summation and integrated with the fourth order Hermite predictor-corrector method with the block timesteps. For long-...

We describe a family with autosomal dominant inheritance of increased body iron stores characterized by raised serum ferritin concentration and normal transferrin saturation. Liver biopsy showed iron deposition in Kupffer cells without fibrosis. The clinical features of HFE-related hemochromatosis were absent, as were the Cys282Tyr and His63Asp mutations. Venesection therapy was poorly tolerate...

We report the sequences of two genomic regions from the pathogenic yeast Candida glabrata and their comparison to Saccharomyces cerevisiae. A 3 kb region from C. glabrata was sequenced that contains homologues of the S. cerevisiae genes TFB3, MRPL28 and STP1. The equivalent region in S. cerevisiae includes a fourth gene, MFA1, coding for mating factor a. The absence of MFA1 is consistent with C...

Universal topological properties of two-dimensional trivalent cellular patterns are found from shell analysis of soap froth and computer-generated Voronoi diagrams. We introduce a cluster analysis based on the shell model and find the universal relation ln(a/mu(2)) = A+Bln(mu(2)), with the generalized Aboav parameter a and second moment of the number of cell edge distribution mu(2). For the sec...

We describe a family with autosomal dominant inheritance of increased body iron stores characterized by raised serum ferritin concentration and normal transferrin saturation. Liver biopsy showed iron deposition in Kupffer cells without fibrosis. The clinical features of HFE-related hemochromatosis were absent, as were the Cys282Tyr and His63Asp mutations. Venesection therapy was poorly tolerate...

This article is a pedagogical piece on hierarchical cluster analysis, a method for investigating the structure underlying data. Such methods are useful for finding similar groups of cases in data sets when it is not known a priori how many groups are present. The article is laid out asfollows: First, a brief history and overview of the methods is presented; second, an illustrative example with ...

Feature extraction is the process of eliminating the irrelevant information and redundant features during Data Mining. Of all the existing feature subset selection algorithms, most of them can effectively eliminate irrelevant features but fail to handle redundant features. The Improved FAST eliminates irrelevant features first and from the result set it removes the redundant features. The Impro...