OBJECTIVE We investigated whether preeclampsia is a risk factor for cochlear damage and permanent hearing loss. STUDY DESIGN Prospective case-control study design. SETTING Academic tertiary medical center. PATIENTS Subjects included 40 patients with preeclampsia and 30 healthy pregnant women. INTERVENTIONS Otoscopic examinations and pure-tone audiometry, tympanometry, otoacoustic emissi...

HYPOTHESIS To investigate the intracochlear micromorphology with regard to frequent patterns of cochlear electrode insertion trauma. OBJECTIVE Cochlear implantation is a widely accepted treatment for deafness and high-grade sensorineural hearing loss. Although the device and the implantation methods are continuously optimized, damage of intracochlear structures due to electrode insertion is a...

OBJECTIVE To quantitatively demonstrate and classify the histopathologic changes in the cochlea of the human temporal bones with labyrinthitis ossificans (LO). STUDY DESIGN Comparative human temporal bone study. SETTING Tertiary academic medical center. SUBJECTS AND METHODS We compared 23 temporal bone specimens from 19 deceased donors with LO associated with the round window membrane (RW...

Background: The number of children with cochlear implants who have other difficulties such as attention deficiency and cerebral palsy has increased dramatically. Despite the need for information on the results of cochlear implantation in this group, the available literature is extremely limited. We, therefore, sought to compare the levels of auditory perception in children with cochlear implant...

For decades, we have presumed the death of hair cells and spiral ganglion neurons are the main cause of hearing loss and difficulties understanding speech in noise, but new findings suggest synapse loss may be the key contributor. Specifically, recent preclinical studies suggest that the synapses between inner hair cells and spiral ganglion neurons with low spontaneous rates and high thresholds...