OBJECTIVE To investigate the potential value of postoperative concurrent chemoradiation among patients with high-risk salivary gland carcinomas. DESIGN Case control study based on retrospective medical record review. SETTING A tertiary care comprehensive cancer center. PATIENTS A total of 24 patients, 12 with major salivary gland carcinoma who were treated with postoperative concurrent ch...

BACKGROUND The introduction of preoperative chemoradiation into the treatment protocol of rectal adenocarcinomas has affected the microscopical morphology in subsequent resection specimens. The constellation of histopathological changes is varied and well documented. AIM To describe oncocytic change in rectal cancers that have been treated with chemoradiation before surgery. METHODS 7 of 54...

Chemoradiation therapy is widely used to treat both inoperable and operable patients, and is less invasive than surgery. Although the number of long-term survivors who have received chemoradiation therapy is increasing, the long-term toxicity pattern and cumulative incidence of toxicity regarding this modality are poorly understood. Classically, chemoradiation therapy for esophageal cancer cons...

BACKGROUND In the past, surgeons believed that in order to eradicate regional disease, a radical or modified radical neck dissection was necessary. An evolution in surgical principles and the popularization of primary chemoradiation has raised the questions regarding the role of neck dissection and the extent of neck dissection following therapy. The aim of this study was to determine the effic...

Background: Conventional cancer treatment is associated with resistant cancer development, treatment and quality of life limiting adverse effects, and patients’ inability to complete intended treatment plans. Conventional cancer treatment’s adverse effects lead 36.1% of cancer patients to seek integrative cancer treatments, which can provide a 15 percentage-point improvement in their health sta...

The treatment of anal squamous cell cancer with definitive chemoradiation is the gold-standard therapy for localized anal cancer, primarily because of its sphincter-saving and colostomy-sparing potential. Studies have addressed different chemoradiation regimens in hopes of improving on the standard protocol of fluorouracil (5-FU), mitomycin, and radiation, but no alternative regimens have prove...

Background: Cervical cancer is the second most common malignancy among women in India. The standard of treatment for locally advanced lesions Concurrent Chemoradiation with External Beam Radiotherapy followed by Intracavitary Brachytherapy (GEC-ESTRO). dose received entire vagina cannot be accurately measured a vaginal point assessment at level ovoids alone. Aims and Objectives: Our study aims ...

Locally advanced non-small-cell lung cancer is a heterogeneous group of diseases encompassing both stage IIIA and IIIB disease. The treatment options vary, including surgery, chemotherapy, neoadjuvant concurrent chemoradiation, definitive chemoradiation, radiation, and various combinations of the above. Optimal therapy for each patient group is controversial; however, previous trials have shown...

Treatment of locally advanced pancreatic cancer is challenging. Despite continuing research, effective treatments continue to be elusive with median survival of only 8-12 months. Treatment options for locally advanced pancreatic cancer include radiation therapy, concurrent chemoradiation or chemotherapy. It is felt that radiation therapy is a suboptimal treatment as most of patients will die of...