The first electrochemical series in a deep eutectic solvent (DES) is described. Speciation resulting from the unusual chemistry of the choline chloride based DES is used to explain both similarities and differences from aqueous media. We give examples of how these differences can be exploited in technologically important systems.

The results of liver perfusion experiments of Guggenheim and Loeffler (2) suggested that choline is oxidized to betainealdehyde (formylmethyltrimethyl ammonium ion). The products of reactions in vitro (3-6) exhibited the properties of betainealdehyde and betaine. It was shown that these products are formed by two enzymes of rat liver (7), choline oxidase of mitochondria (8, 9), and betainealdeh...

The Cover Feature illustrates the distribution of different components aqueous choline chloride solution around hydrophobe methane. hydrogen bonds formed between water molecules, cations, and ions are shown using light yellow dots. preferred orientations with respect to methane at distances from latter quantified in a 2D histogram. More information can be found Research Article by Rajarshi Chak...

Interfacial behavior of selected biologically and technologically relevant ions is studied using molecular dynamics simulations employing polarizable potentials. Propensities of choline, tetraalkylammonium (TAA), and sodium cations, and sulfate and chloride anions for the air/water interface are analyzed by means of density profiles. Affinity of TAA ions for the interface increases with their i...

BACKGROUND Homozygosity for the variant 677T allele in the methylenetetrahydrofolate reductase (MTHFR) gene increases the requirement for folate and may alter the metabolic use of choline. The choline adequate intake is 550 mg/d for men, although the metabolic consequences of consuming extra choline are unclear. OBJECTIVE Deuterium-labeled choline (d9-choline) as tracer was used to determine ...

The isolation of phosphatidyl choline which contains all of its nitrogen as choline, phosphorus as glycerophosphate, and has a relatively high iodine number, has posed a problem for some time. The most widely used method has been that of Levene and Rolf (l), as modified by Pangborn (24), wherein this lipide is isolated through a cadmium chloride complex. Sinclair (5) has described a procedure f...

Natural deep eutectic solvents (NADESs) considered as “green” solvents offer an efficient, safe, sustainable, and cost effective method alternative to conventional extraction while microwave assisted extraction (MAE) is a convenient, rapid, environmental friendly and efficient technique. The combination of NADESs with MAE was applied in this study for the recovery of phenolic compounds from oli...

A combination of the methods described by Schultz et al. (6) and by Ussing and Zerahn (9) was used to measure directly the unidirectional uptake of sodium from the outside solution into the frog skin, under short-circuit conditions. The sodium uptake was determined at six sodium concentrations ranging from 3.4 to 114 mM. NaCl was replaced by choline chloride in the solutions bathing both sides ...

Carassius auratus placed in a dilute sodium chloride solution (400 gM) is able to absorb sodium and chloride ions at very different rates, or to absorb one ion and to lose the other. This is the case not only for fish which have been previously kept in choline chloride or sodium sulfate solutions or deionized water, in order to stimulate their absorption processes, but also in control fish whic...

Acid hydrolysis of dehulled soybean meal (SBM) and corn gluten meal (CGM) followed by chromatographic amino acid analysis (ninhydrin detection) revealed substantial quantities of S-methylmethionine (SMM) in both ingredients (1.65 g SMM/kg SBM; 0.5 g SMM/kg CGM). Young chicks were used to quantify the methionine- (Met) and choline-sparing bioactivity of crystalline L-SMM, relative to L-Met and c...