Background . Metastatic liver injury is a distinct oncological problem, irrespective of primary malignancy. Resection surgery not always feasible in such patients. Isolated chemoperfusion promising treatment option multiple small-focal metastatic organic lesions. This technique technically complex, which limits its broader evaluation and adoption clinical practice. The diversity isolated techni...

PURPOSE The ICECAP-A and EQ-5D-5L are two index measures appropriate for use in health research. Assessment of content validity allows understanding of whether a measure captures the most relevant and important aspects of a concept. This paper reports a qualitative assessment of the content validity and appropriateness for use of the eq-5D-5L and ICECAP-A measures, using novel methodology. ME...

Background and objective:Medicine is a combination of health and healingthat includes diagnosis, treatment and prevention of disease and many other aspects of health. Despite the fact that many improvements have been made in medical education, medical schools continue to face many problems in facing the community, patients, doctors And students who are not compatible with the s...

Although the product-centered focus of life-cycle assessment has been one of its strengths, this analytical perspective embeds assumptions that may conflict with the realities of environmental problems. This ar ticle demonstrates, through a series of mathematical derivations, that all the products in use, rather than a single product, frequently should be the appropriate unit of analysis. Such ...

Arsenic is a naturally occurring toxic metal and its presence in food could be a potential risk to the health of both humans and animals. Prolonged ingestion of arsenic contaminated water may result in manifestations of toxicity in all systems of the body. Visual Analytics is a multidisciplinary field that is defined as the science of analytical reasoning facilitated by interactive visual inter...

Phase 1 of the IARPA program ICArUS (Integrated Cognitive-neuroscience Architectures for Understanding Sensemaking) requires a challenge problem that poses cognitive challenges of geospatial sensemaking (BAA, 2010). The problem serves as a modeling challenge for performers and enables assessment in T&E (Test and Evaluation) per BAA guidelines. This document describes the Phase 1 challenge probl...

this study attempts to answer the question of distinguishing appropriate intensity measure parameter for performance-based design or assessment, taking into account the efficiency aspect. the comprehensive comparative tables proposed in this paper could be an effective support in the decision making procedure for intensity measure selection, comprising most of the frequently utilized intensity ...

.............................................................................................................................................2 Introduction: ........................................................................................................................................2 1. Substantial equivalence, familiarity and comparative assessment.......................................