THE WASSERMANN REACTION (C.L.W.R.) The original Wassermann test was a complement-fixation test which used as the antigen treponema from the liver of a syphilitic stillborn child (Bordet, Gengo^ Wassermann, 1906). Although the true Wassermann test is no longer carried out it15 not uncommon for the term to be used as a generic expression for any complement' fixation test using heart extract as th...

In a previous publication (Sen Gupta, 1943), the results of the complement-fixation test using the original Witebsky, Klingenstein, Kuhn (WKK) antigen were reported. Reference was also made about the preparation of the antigen according to the WKK method. It was shown that a complement-fixation test of marked degree of ' specificity' for kala-azar had been evolved. In order to investigate furth...

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1. A specific complement fixation reaction test for Plasmodium knowlesi malaria in rhesus monkeys is reported with details involved in the preparation of the antigen and procedures employed in setting up the test. 2. It was found that specific complement-fixing antibodies appeared early in the course of the experimental disease and persisted during the course of the chronic infection. 3. The fi...

Rabbit and cow anti-Streptococcus dysgalactiae sera were tested by bacterial agglutination, complement fixation, hemagglutination, and immunodiffusion for the presence of antibody. The results of these tests were compared with mouse-protection studies on the same serum to estimate which in vitro test would best reflect the in vivo protective capacity of serum. Identification of the antibody con...