In studies of complex health conditions, mixtures of discrete outcomes (event time, count, binary, ordered categorical) are commonly collected. For example, studies of skin tumorigenesis record latency time prior to the first tumor, increases in the number of tumors at each week, and the occurrence of internal tumors at the time of death. Motivated by this application, we propose a general unde...

exist. We shall prove that under certain conditions we obtain (1) as a limit distribution of double sequences of independent and infinitesimal random variables and apply this theorem to stochastic processes with independent increments. Theorem 1 Let ξn1, ξn2, . . . , ξnkn (n = 1, 2, . . .) be a double sequence of random variables. Suppose that the random variables in each row are independent, t...

Abstract Objective To estimate the prevalence and factors associated with worsening of frailty in older people arterial hypertension. Methods Quantitative, longitudinal, prospective analytical study. Carried out community-dwelling hypertensive from Minas Gerais. Sampling was probabilistic, by clusters two stages. Data collection took place at people's homes moments. Demographic, socioeconomic c...

The failure processes of heterogeneous repairable systems with minimal repair assumption can be modelled by nonhomogeneous Poisson processes. One approach to describe an unobserved heterogeneity between is multiply the intensity function a positive random variable (frailty term) gamma distribution. This assumes that relative frailty distribution among survivors independent age. Where are being ...