The reconstruction of the atrophic alveolar ridges for implant placement is today a common procedure in dentistry daily practice. The surgical reconstruction provides for the optimization of the supporting bone for the implants and a restoration of the amount of keratinized gingiva for esthetic and functional reasons. In the past, tissue regeneration has been performed with autogenous bone and ...

statement of problem: various surgical procedures have been used to achieve root coverage and subepithelial connective tissue graft (sctg) is identified as one of the most successful techniques. recently, acellular dermal matrix allograft (adma) has been developed as a substitute for sctg to avoid removing the palatal connective tissue. purpose: the present study compared the clinical efficienc...

the b cell is a vital contributor to humoral immunity. the b cell-specific antigen cd20 is expressed during b cell development, starting at the pre-b cell level and persists through b cell differentiation, but is lost during terminal differentiation to plasma cells. rituximab is a monoclonal antibody that destroys both normal and malignant b cells that have cd20 on their surfaces and is therefo...

bone has a capability to repair itself when it is fractured. repair involves the generation of intermediatetissues, such as fibrous connective tissue, cartilage and woven bone, before final bone healing can occur. theprocess of cartilage-to-bone transition (cbt) is a key for the achievement of rigid bone healing duringfracture repair. we tested this potential for elastic cartilage using a long ...

The primary aim of this randomized clinical investigation was to evaluate gingival recession defects treated by a coronally advanced flap and sub-epithelial connective tissue graft (SCTG) with or without enamel matrix derivative (EMD). Twelve patients with Miller's class III buccal recession defects of ≥2.0 mm in similar contra lateral sites were included in this split-mouth randomized study. T...

The American Academy of Periodontology 1 has defined marginal tissue recession as an acquired deformity with the gingival margin being located apical to the cementoenamel junction (CEJ), resulting in exposed root surface and loss of attached gingiva. Gingival recession is a common feature in populations with high as well as poor standards of oral hygiene 2 . Many factors have been proposed to i...

Late loss of allograft function is primarily attributed to chronic rejection (CR). There are no effective treatments for CR and the underlying cause of the disease is unknown. This study compared events that occurred within cardiac allografts placed in mice that received either anti-CD4 therapy and develop CR or anti-CD40L therapy and do not develop CR. Both TGFbeta and connective tissue growth...

This case report is focused on the possibility of treating atrophic ridge with a reduced number of surgical procedures and a reduced healing time. A 43-year-old female patient affected by edentulism associated with horizontal resorption of the ridge was treated by means of a sagittal osteotomy and expansion of the ridge with the new modified edentulous ridge expansion (MERE) technique to obtain...

Extracts from fresh normal human connective tissue (rectus sheath) exhibited a decided inhibiting action on grafts of Rat Tumor 256 transplanted into test animals. There was complete inhibition of tumor growth in 66 per cent of the animals; there was a marked retardation in the rate of growth in another 15 per cent, the tumors in these instances being much smaller than the controls transplanted...

The decrease of immunogenicity is a priority requirement to pre-implantation treatment of the xenogeneic graft tissue. To create tissue implants of the pericardium and aortic valve leaflets, we have developed a method of devitalizing treatment, based on the combined effect of low temperatures (-196 °C) and ionizing β-radiation. This approach provides deletion to the main targets of biomaterial ...