background & aim:breast cancer is the second most common cancer in women after lung cancer. given that the herbal ingredients are used for centuries to treat cancer,the aim of this study was to determine the cytotoxic effect of hydroalcholic extract from thymus daenesiscelak on mcf-7 cancer cells line. experimental: breast cancer cells mcf-7 and natural fibroblast cells were cultured in dmem me...

Background: The direct effect of some opioids on immune cells has been demonstrated. The aim of this study was to assess the apoptotic effect of opium on Jurkat T lymphocyte cells. Methods: Different concentrations of opium (2.86 × 10-3 to 2.86 × 10-11 g/ml) were added to 24-well plates containing 5 × 105 Jurkat cells. Apoptotic events were assessed after 6, 24, and 72 hours by flow-cytometric...

fluoxetine is a common antidepressant which selectively inhibits serotonin reuptake at synaptic level. some research findings have proposed the effect this drug on neurogenesis, neuronal survival as well as proliferation of the neural progenitor cells. endometrium is a part of uterus which harbors mesenchymal stem cells. this source of stem cells can be differentiated into neural cells which ma...

kcnk2 was previously shown to regulate immune-cell trafficking into the central nervous system (cns). kcnk2-/- mice demonstrated a more severe disease course in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis, due to an increased immune-cell migration into the cns. an upregulation of the cellular adhesion molecules icam1 and vcam1 on brain endothelial cells in k...

A 60-day trial with six diets (three different protein levels × two different lipid levels) containing 30, 35 and 40% protein with 10 and 15% lipid levels was conducted to determine the optimum dietary protein to lipid ratio and effects on growth performance and hematological indices of Aspikutum, Leuciscus aspius female×Rutilus frisii male. Two hundred and fifty two fish (31.2±0.4 g; mean±SEM)...

Cell damage induced by free radicals has been implicated as causal factor in a wide variety of human diseases such as cancer, neurodegenerative disorders. Scientific recognition of natural antioxidants may be helpful in preventing many diseases. Aqueous Date fruit extract (ADFE)- PC12 cell line. ADFE at concentrations of 0.1-10% containing 0.005% H2O2 and H2O2 at concentrations of 0.01-1% conta...

Background: Many of the multiple traumatized patients who refer to the hospital need transfusion. Transfusion-related acute lung injury (TRALI) is a serious clinical syndrome associated with the transfusion of plasma-containing blood components. In the article, we present a case of TRALI following transfusion of packed red blood cells Case Presentation: A 24 year old male referred to Shahid Beh...

introduction: an investigation of bone, cartilage and fat differentiation potentials of canine bone marrow-derived mesenchymal stem cells. materials and methods: bone marrow aspirates were obtained from 10 canine’s iliac crest under general anesthesia. each sample was separately loaded on lymphodex and centrifuged at 1200 rpm for ten minutes to obtain mononuclear cell fraction. 5×104 cell/cm2 o...