background: sustainable and commercial production of taxol as an anti cancer drug is a critical point to its clinical application. nowadays, hazel because of rapid growth and wide range distribution is considered as an alternative source of taxol. objective: to increase taxol production the cdna encoding 3-hydroxy-3-methylglutaryl-coa reductase (hmgr) from iranian hazel (genebank accession numb...

results the results revealed the formation of spherical silver nanoparticles with an average size of 10 nm. moreover, concentration of snps in a 25 ml sample containing both snps and plant extract biomass was 2.934 mg/l on average. serial microdilution test showed that snps at the concentration of 50 μg/ml can inhibit growth of the pathogen. conclusions the present study extends the existing li...

in the present study, four carbon sources were tested for the polyester synthesis of pseudomonas aeruginosa pa01 which is a ubiquitous environmental bacterium and is one of the top three causes of opportunistic human infections. these included linear c8 to c11 carboxylic acids. octanoic acid, nonanoic acid, decanoic acid and undecanoic acid were added to m1 minimal medium to final concentration...

K. pneumoniae is the predominant pathogen isolated from liver abscesses of diabetic patients in Asian countries. Although elevated blood glucose levels cause various immune problems, its effects on K. pneumoniae virulence are unknown. This study investigated the regulation of capsular polysaccharide (CPS) biosynthesis, a major determinant for K. pneumoniae virulence, in response to exogenous gl...

in the present study, a simple, efficient and fast synthetic strategy was reported for the green biosynthesis of silver nanostructures (i.e. nanoroads and nanoparticles) by the extract of suaeda acuminata plant, without any catalyst, template or surfactant. aqueous extracts were obtained by maceration and microwave assisted extraction (mae) methods. in mae procedure, the effect of microwave pow...

nowadays, green chemistry and its advantages are generating interest of researchers toward ecofriendly biosynthesis of the metallic nanoparticles. in this research, a rapid, simple and green method was developed for the synthesis of silver nanoparticles using aqueous extract of prangos ferulaceae leaves. the synthesized silver nanoparticles were characterized by uv-vis spectroscopy, scanning el...

nanomaterials (nms) are widely used in health and biomedical applications, however, only a few studies investigate their toxic effects.  the present report signifies a contribution to the study of the toxic effects of silver nanoparticles (ag nps)  on   e. coli cells, which is a model organism of anthropogenic pollution. the toxicity of nanoparticles depends on their  chemical and surface prope...

recently, biosynthesis of nanoparticles has received attention due to an increasing need of developing rapid, simple and ecofriendly protocol. pathogenicity of some of the organisms and lengthy reaction are the drawbacks involved with biosynthesis. we describe a simple protocol for rapid synthesis of silver nanoparticles through biological route using a marine-derived fungus aspergillus niger. ...

Quorum sensing through farnesol, a quorum sensing molecule, regulates virulence and morphogenesis in Candida albicans. Farnesol and high cell density of C. albicans repress hyphal formation in a minimal medium containing N-acetyl-D-glucosamine. Global transcription profiling at an early stage of quorum sensing by C. albicans in the N-acetyl-D-glucosamine medium was analyzed. Twenty-two of a tot...