background: the role and proper dose of pralidoxime in the treatment of organophosphorus (op) compounds poisoning is an unresolved issue .this study was designed to compare the regimen recommended by the world health organization (who) with the commonly used standard regimen of pralidoxime. methods: this was a randomized open labeled prospective study on op poisoned patients admitted to jss hos...

to evaluate the effect of adding neoadjuvant chemotherapy to surgery and radiation therapy for locally advanced resectable oral cavity squamous cell carcinoma, 24 patients with t3 or t4a oral cavity squamous cell carcinoma were randomly assigned to surgery alone or docetaxel, cisplatin, and 5-fu (tpf) induction chemotherapy followed by surgery. all patients were planned to receive chemoradiothe...

labor pain is a cause of stress and suffering; for which many women seek methods to relieve this pain. the aim of this study was to determine the effect of relaxation techniques on pain relief during labor. this study was carried out on 62 pregnant women referred to fatemieh hospital (hamadan, iran) during their labor. they were selected using convenience sampling and were divided randomly in t...

gliobalstoma multiforme (gbm) or grade 4 astrocytoma is the most malignant form of primary brain tumor. treatment of glioblastoma is difficult despite of surgery, radiotherapy and chemotherapy. patients with glioblastoma survive for less than 12 months. considering to biology function of glioblastoma, researchers have recently offered new therapeutic approaches such as cannabinoid therapy for g...

conclusions this method is recommended for the treatment of dermal warts, owing to the effectiveness, short duration of treatment, and low cost of topical treatment for dermal warts using hd tablets. background warts are common dermatological lesion caused by skin epithelial cells’ infection with human papillomavirus (hpv). objectives this study aimed to assess the efficacy of a new method for ...

the aim of this study was to assess the efficacy and tolerability of the aqueous extract of echium amoenum in combination with ssris in patients with general anxiety disorder (gad). the study was an 8-week double-blind randomized clinical trial. thirty-seven adult outpatients who met the dsm-iv-tr criteria for gad based on the structured clinical interview participated in the trial. in this stu...

topical retinoids are considered as the first line therapy in the treatment of acne vulgaris, but they are associated with cutaneous irritation. in this study, isotretinoin-loaded solid lipid nanoparticles(it-sln) were prepared to treat the mild to moderate acne. also using it-sln would minimize it adverse effects in comparison to commercial product, isotrex®. this study was conducted to prepar...

aim and background: patients with ischemic heart disease in acute stage experienced great anxiety and in compared with patients had less anxiety were affected 5 times more to ischemia, re-infarction, tachycardia, arrhythmias and ventricular fibrillation.  excessive anxiety delays recovery and increases the probability of their death in the first month. numerous studies have shown that heart dis...

normal 0 false false false en-us x-none ar-sa background: high prevalence of obesity and the importance of this issue as a risk factor for chronic diseases such as severe cardiovascular diseases, diabetes, and cancer necessitate the need for treatment. the aim of this study was the evaluation of acarbose effect on the weight loss in non-diabetic overweight or obese patients in kerman. materials...

primary dysmenorrhea refers to painful cramps during menstruation with no organic reason. with respect to its high incidence and adverse outcomes in quality of life and some evidences regarding the sedative and antispasmodic effects of melissa officinails on smooth muscles as an herb, this double-blind clinical trial was conducted to determine the effects of its capsules on severity of dysmenor...