The development of molecule-based switchable multifunctional materials remains an important challenge in molecular science. In particular, achieving high proton conductivities spin crossover (SCO) compounds is significant interest as the state can be controlled via transfer induced by electric field, which leads to magnetoelectric effects and spintronics. However, best our knowledge, no studies...

The P2Y(1) ADP receptor activates G(q) and causes increases in intracellular Ca(2+) concentration through stimulation of PLC. In this study, we investigated the role of the amino acid residues in the COOH terminus of the human P2Y(1) receptor in G(q) activation. Stimulation of Chinese hamster ovary (CHO-K1) cells stably expressing the wild-type human P2Y(1) receptor (P2Y(1)-WT cells), P2Y(1)-De...

Hydrogen sulfide (H2S), is a relevant mediator in cardiovascular physiology. Indeed, impaired production of H2S contributes to the pathogenesis of important cardiovascular disorders [1]. Accordingly, exogenous compounds, acting as H2S-releasing agents, are viewed as promising therapeutic agents for cardiovascular diseases. Thus, this work aimed at evaluating the H2S-releasing properties of the ...

This investigation examines the role of carboxyl functionalized multi-walled carbon nanotubes (COOH-MWCNTs) in the on- and off-axis flexure and the shear responses of thin carbon woven fabric composite plates. The chemically functionalized COOH-MWCNTs were used to fabricate epoxy nanocomposites and, subsequently, carbon woven fabric plates to be tested on flexure and shear. In addition to the n...

The study investigated the photochemical transformation of carboxylated multiwalled carbon nanotubes (COOH-MWCNTs), an important environmental process affecting their physicochemical characteristics and hence fate and transport. UVA irradiation removed carboxyl groups from COOH-MWCNT surface while creating other oxygen-containing functional groups with an overall decrease in total surface oxyge...

The present study was undertaken to determine the extent of COOH-terminal proteolytic processing in matrix Gla protein (MGP), a 10-kDa protein which contains 5 residues of the vitamin K-dependent Ca2+ binding amino acid, gamma-carboxyglutamic acid (Gla). Two forms of MGP were isolated from demineralization and urea extracts of bovine cortical bone, one 79 residues in length with the COOH termin...

An efficient and reliable electrochemical sensing platform based on COOH-fMWCNTs modified GCE (COOH-fMWCNTs/GCE) was designed for the detection of nanomolar concentration Nile Blue Sulphate (NBS). In comparison to bare GCE, scaffold considerably enhanced peak current response NBS dye as confirmed from results voltammetric investigations. The approach detecting in droplet its solution dried over...

Mutations in the Escherichia coli lpp gene resulting in the alterations of the COOH-terminal region of the lipoprotein have been isolated by oligonucleotide-directed mutagenesis. As might be expected, substitution of Lys78 with Arg78 completely abolished the formation of murein-bound lipoprotein. Each of the following single amino acid substitutions did not significantly affect the formation of...