The favorable nuclear properties of rhenium-188 for therapeutic application are described, together with new methods for the preparation of high yield and stable 188Re radiopharmaceuticals characterized by the presence of the nitride rhenium core in their final chemical structure. 188Re is readily available from an 188W/188Re generator system and a parallelism between the general synthetic proc...

Radiopharmaceuticals are radioactive compounds that are prepared by a radiopharmasist and used in Nuclear Medicine departments for diagnostic or therapeutic purposes of human diseases. They are generally used i.v. so they have to be sterile and apyrogenic like other parenteral drugs. Effecting in a correct way and localising in the desired tissue with a sufficient amount, physicians and Nuclear...

122 patients who presented with or developed calcification within metastatic ovarian cancer. Changes in soft tissue lesion size and the development of calcification have been correlated with histopathology and outcome. The study group was compared with a control group of 1577 patients who had a CT scan performed at least once during follow-up. A positive relationship between calcification and t...

Medical application of ionizing radiation and radioactive isotopes were considered almost immediately after their discovery. The intense research interest in radioactivity, materials structure, subatomic particles and in the establishment of physical principles resulted in milestone inventions such as the radiotracer principle, particle accelerators, nuclear reactors and detectors sensitive eno...