Magnetic iron oxide nanoparticles were obtained for the first time via green chemistry approach, starting from two aqueous extracts of wormwood (Artemisia absinthium L.), both leaf and stems. In order to obtain magnetic suitable medical purposes, more precisely with hyperthermia inducing features, a synthesis reaction was conducted, at room temperature (25 °C) 80 °C, formulations precipitation ...

We present a proof of concept on the use of thermomagnetic polymer films (TMFs) as heating devices for magnetic hyperthermia in vitro. The TMFs were prepared through spray assisted layer-bylayer assembly of polysaccharides and magnetic iron oxide nanoparticles, yielding an alternate magnetic-polymer multilayer structure. By applying a remote alternating magnetic field (AMF) (f = 180 kHz; H = 35...

BACKGROUND Induction heating devices using the induction coil and magnetic nanoparticles (MNPs) are the way that the magnetic hyperthermia is heading. OBJECTIVE To facilitate the induction heating of in vivo magnetic nanoparticles in hyperthermia experiments on large animals. METHODS An induction heating device using a planar coil was designed with a magnetic field frequency of 328 kHz. The...

Magnetic-nanoparticle-mediated intracellular hyperthermia has the potential to achieve localized tumor heating without any side effects. The technique consists of targeting magnetic nanoparticles to tumor tissue followed by application of an external alternating magnetic field that induces heat through Néel relaxation loss of the magnetic nanoparticles. The temperature in tumor tissue is increa...

Magnetic nanoparticles (MNPs) have demonstrated their great potentials in medical applications. Technology advancements in synthesis and modification of nanoscale materials have advanced the development of different medical applications of MNPs. This paper reviews the main chemical and physical properties of MNPs important in medical applications. Pharmacokinetics and cellular adsorb of MNPs ar...

Magnetic nanoparticle-conjugated polymeric micelles (MNP-PMs) consisting of poly(ethylene glycol)-poly(lactide) (PEG-PLA) and iron oxide nanoparticles were prepared and used as nanocarriers for combined hyperthermia and chemotherapy. Doxorubicin (DOX) was encapsulated in MNP-PMs, and an alternating magnetic field (AMF) resulted in an increase to temperature within a suitable range for inducing ...

Magnetic nanoparticles (MNPs) have been widely used to increase the efficacy of chemotherapeutics, largely through passive accumulation provided by the enhanced permeability and retention effect. Their incorporation into biopolymer coatings enables the preparation of magnetic field-responsive, biocompatible nanoparticles that are well dispersed in aqueous media. Here we describe a synthetic rou...

Colloidal nanocrystal assemblies (nanoclusters), consisting of 13 nm iron oxide nanocrystals, were synthesized in various sizes (45-98 nm), and were investigated as heating mediators for magnetic particle hyperthermia. The colloidal nanocrystal clusters show enhanced heating efficiency in comparison with their constituent primary iron oxide nanocrystals due to collective magnetic features. The ...

Extensively investigated and mutagenized Cow Pea Mosaic Virus (CPMV) has been demonstrated in a variety of nanoassemblies. Iron Oxide (IO) has the potential to surpass limits of detection in bioimaging applications. Particularly g-Fe2O3 (maghemite) is considered as one of the most desirable materials for technological and biomedical applications due to its inherent biocompatible nature. Additio...

Abstract Magnetic spinel ferrite nanoparticles (SFNPs) attract high scientific attention from researchers due to their broad area for biomedicine applications, comprising cancer magnetic hyperthermia and targeted drug delivery. Uniquely, its excellent performance, namely, tuning size surface morphology, magnetism, extraordinary magnetically heat induction, promising biocompatibility, specific t...