Carbon monoxide releasing molecules (CORMs) have been suggested as a new synthetic class of antimicrobials to treat bacterial infections. Here we utilized a novel EBOR-CORM-1 ([NEt4][MnBr2(CO)4]) capable of water-triggered CO-release, and tested its efficacy against a collection of clinical Pseudomonas aeruginosa strains that differ in infection-related virulence traits. We found that while EBO...

The present study deals with phytochemical and anthelmintic evaluation of corm of Amorphophallus campanulatus. This evaluation revealed the presence of many phytochemical constituents. Corm was extracted with petroleum ether, chloroform and methanol. Crude tannins were isolated from methanol extract. All extracts and crude tannins were evaluated for anthelmintic activity. Chloroform, methanol e...

Background Besides nitric oxide, carbon monoxide (CO) also activates soluble guanylyl cyclase (sGC). CO as well as the CO-donor CORM-2 have been shown to possess vasodilatory properties. Whether these vasodilatory properties by CO can be attributed to sGC activation is still a matter of debate. The aim of this study was to examine the involvement of sGC and its different subunits in CO and CORM...

Objective: Taro (Colocasia esculenta L. Schott) is a perennial root crop that belongs to Araceace family.  It is widely cultivated as a staple food in Africa, Asia and pacific Islands. Despite its importance, there is limited information on many aspects of the crop. In order to obtain data that can support improved and sustainable taro production, a field trial was conducted to study t...

We have designed and synthesised a [Ru(CO)3 Cl2 (NAC)] pro-drug that features an N-acetyl cysteine (NAC) ligand. This NAC carbon monoxide releasing molecule (CORM) conjugate is able to simultaneously release biologically active CO and to ablate the concurrent formation of reactive oxygen species (ROS). Complexes of the general formulae [Ru(CO)3 (L)3 ](2+) , including [Ru(CO)3 Cl(glycinate)] (CO...

explants of leaves, petals, anthers, styles and ovaries of c. speciosus, c. cancellatus, c. gilanicus and c. almehensis were cultured on ls media with three different combinations of naa and bap in the dark. callus and neoformant organs (leaf and corm-like structure and ordinary and contractileroots) were fomd on some of these explants. corm explants from these species were also cultured on ms ...

Ang II has been involved in the pathogenesis of cardiovascular diseases, and matrix metalloproteinase-9 (MMP-9) induced migration of human aortic smooth muscle cells (HASMCs) is the most common and basic pathological feature. Carbon monoxide (CO), a byproduct of heme breakdown by heme oxygenase, exerts anti-inflammatory effects in various tissues and organ systems. In the present study, we aime...

To develop saffron planting in Urmia, West Azerbaijan, Iran, a split-split plot experiment based on CRBD was carried out in the Urmia University's research farm for two years (2013-14). Nanofertilizers (Fe, P, K and nofertilizer (control)) as main plots, saffron ecotypes (Mashhad, Torbat-Heydarieh, Torbat-jam, Gonabad, Ghaen and Birjand) as subplots and maternal corm weight (6, 8, 10 and 12 g) ...

Sagittaria trifolia is a good model of wetland plants to elucidate the formation of corm. However, few studies have been conducted to uncover the complexity of gene expression involved in corm formation. In this study, high-throughput tag-sequencing based on Solexa Genome Analyzer Platform was applied to monitor the changes in gene expression with three libraries of differentially expressed gen...

The product organ (storage organ; corm) of the Chinese water chestnut has become a very popular food in Asian countries because of its unique nutritional value. Corm formation is a complex biological process, and extensive whole genome analysis of transcripts during corm development has not been carried out. In this study, four corm libraries at different developmental stages were constructed, ...