AIMS To investigate the clinical characteristics and compare the effects of several methods of treatment of Mooren's corneal ulcer. METHODS 550 consecutive cases of Mooren's corneal ulcer were analysed in patients, including age, sex, laterality of eye, ulcer location, perforative rate, cure rate of surgeries, recurrent rate, the effects of conjunctiva excision, lamellar keratoplasty (LKP), a...

Purpose: To describe a case of polymicrobial keratitis and endophthalmitis successfully treated with topical and systemic antibacterial and antifungal agents, collagen cross-linking (CXL) and penetrating keratoplasty. Methods: Case report Results: A 59-year-old woman presented with a corneal ulcer. Multiple samplings of the corneal lesion were used for microbiological investigations by standard...

MOOREN'S ulcer (chronic serpiginous ulcer) of the cornea is described as a superficial corneal ulcer usually occurring in the elderly and eventually spreading over the whole corneal surface. Associated features are pain and lacrimation; iritis may occur and rarely a hypopyon (Duke-Elder, 1959). Initially one or more grey peripheral infiltrates occur; these ulcerate and coalesce. Undermining of ...

Urkude J, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-220973 Description Mooren’s ulcer is a painful peripheral ulcerative keratitis of unknown aetiology. It is rapidly progressive inflammatory destruction of the juxtalimbal corneal stroma with no associated scleritis. Mooren’s ulcer is a diagnosis of exclusion, after ruling out all the relevant systemic and local causes that lead to periphe...

OBJECTIVE To compare the therapeutic effectiveness of a single intrastromal dose of gentamycin, tobramycin, ciprofloxacin and ofloxacin for the treatment of corneal ulcers due to Pseudomonas aeruginosa. METHODS Twelve white female New Zealand rabbits underwent mechanical removal of corneal epithelium; then one drop of salt suspension containing Pseudomonas aeruginosa (75,000,000 colony formin...

Neurotrophic keratitis (also called neurotrophic keratopathy) (NTK) is a degenerative disease of the cornea, accompanied with neurogenic inflammation. It caused by sensitive innervation loss trigeminal nerve and characterized reduced sensitivity cornea retardation its healing process. NTC-causing damage to can occur at different levels-from nucleus terminals located in be ocular systemic diseas...