A pair of female monozygotic twins, one of them affected by the de Lange syndrome is described for the first time. Monozygosity was established by most of the accepted standards in use at the present time. Speculation is offered as to whether the discordance in the manifestation of the syndrome provides any clues for understanding its controversial pathogenesis. In this regard two genetic mecha...

Dragana M. Jović,1,2 Yuri S. Kivshar,3 Cornelia Denz,4 and Milivoj R. Belić2 1Institute of Physics, P. O. Box 57, 11001 Belgrade, Serbia 2Texas A&M University at Qatar, P. O. Box 23874, Doha, Qatar 3Nonlinear Physics Center, Research School of Physics and Engineering, Australian National University, Canberra ACT 0200, Australia 4Institut für Angewandte Physik and Center for Nonlinear Science (C...

M J K de Kleine, A L den Ouden, L A A Kollée, M W G Nijhuis-van der Sanden, M Sondaar, B J M van Kessel-Feddema, S Knuijt, A L van Baar, A Ilsen, R Breur-Pieterse, J M Briët, R Brand, S P Verloove-Vanhorick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

Introduction: Cornelia de Lange syndrome (CdLS) is a rare non-hereditary syndrome. The key diagnosis unique facial features, limb anomalies, and growth retardation. Cardiac defects with gastrointestinal genitourinary anomalies may be associated. Case Presentation: This case of neonatal CdLS that we think interesting due to its association novel congenital heart complex. Conclusions: Patients ha...