Transforming growth factor (TGF) receptor III (TGF R3), or -glycan, binds all 3 TGF ligands and inhibin with high affinity but lacks the serine/threonine kinase domain found in the type I and type II receptors (TGF R1, TGF R2). TGF R3 facilitates signaling via TGF R1/TGF R2 but also has been suggested to play a unique and nonredundant role in TGF signaling. Targeted deletion of Tgfbr3 revealed ...

background: diagnosis of coronary artery disease (cad) in early stages is vital in decreasing mortality by reducing the risk factors. the aim of this study was to investigate the association between erectile dysfunction (ed) and cad. methods: a total of 200 patients were divided into four groups according to their angiography results: group 1 (g1, n = 59): patients with one-vessel disease (1-vd...

Transforming growth factor (TGF)beta receptor III (TGFbetaR3), or beta-glycan, binds all 3 TGFbeta ligands and inhibin with high affinity but lacks the serine/threonine kinase domain found in the type I and type II receptors (TGFbetaR1, TGFbetaR2). TGFbetaR3 facilitates signaling via TGFbetaR1/TGFbetaR2 but also has been suggested to play a unique and nonredundant role in TGFbeta signaling. Tar...

A LTHOUGH coronary angiography had Albeen successfully achieved by a variety of methods,1 it was not until the development of the selective technique that visualization of the coronary vessels became a reliable and sound clinical procedure.2 Mortality and morbidity have proved to be low, and the procedure has gained widespread acceptance and availability. It has become essential for the objecti...

Intravenous dipyridamole thallium imaging is reported to be a safe test with minimal side effects. It has been proposed by some that the test simply dilates the coronary vessels without actually producing myocardial ischemia. In this report, we describe a patient who, following intravenous dipyridamole thallium imaging, developed severe myocardial ischemia which persisted for 90 minutes, requir...

Although cardiovascular magnetic resonance allows the non-invasive and radiation free visualization of both the coronary arteries and veins, coronary vessel wall imaging is still undergoing technical development to improve diagnostic quality. Assessment of the coronary vessels is a valuable addition to the analysis of cardiac function, cardiac anatomy, viability and perfusion which magnetic res...

We studied the changes caused by intravenous injection of nitroglycerin (0.3 to 0.6 mg) and dipyridamole (5 to 10 mg) on the resistance of large and small coronary arteries of dogs. The direction of change in resistance of large conductive vessels (Re) was estimated by dividing the pressure drop from aorta to a superficial branch by the flow in that vessel. The total resistance (RT) in the same...

Research focused on the causes, diagnosis, treatment, and prevention of cardiovascular disease is progressing rapidly.1 Radiology has always played a central diagnostic role, particularly in the coronary vessels. A technique for selectively catheterizing the coronary arteries was developed in 1959, and conventional x-ray coronary angiography is still considered the gold standard for detecting c...