SECONDARY WALL-ASSOCIATED NAC DOMAIN PROTEIN1 (SND1) is a master transcriptional switch activating the developmental program of secondary wall biosynthesis. Here, we demonstrate that a battery of SND1-regulated transcription factors is required for normal secondary wall biosynthesis in Arabidopsis thaliana. The expression of 11 SND1-regulated transcription factors, namely, SND2, SND3, MYB103, M...

The development of predictive mathematical models can contribute to a deeper understanding of the specific stages of bone mechanobiology and the process by which bone adapts to mechanical forces. The objective of this work was to predict, with spatial accuracy, cortical bone adaptation to mechanical load, in order to better understand the mechanical cues that might be driving adaptation. The ax...

The challenges of gathering in-vivo measures of brain anatomy from young children have limited the number of independent studies examining neuroanatomical differences between children with autism and typically developing controls (TDCs) during early life, and almost all studies in this critical developmental window focus on global or lobar measures of brain volume. Using a novel cohort of young...

At extracellular pH values close to their pKa values the weak bases, ammonia and procaine, elicited a series of events in non-activated Xenopus eggs, some of which resembled those normally occurring at fertilization. These included: (1) a transient increase in membrane conductance; (2) modification of the microvilli; (3) thickening of the cortical cytoplasm and displacement of the cortical gran...

Plantar fascia (PF) disorders commonly cause heel pain and disability in the general population. Imaging is often required to confirm diagnosis. This review article aims to provide simple and systematic guidelines for imaging assessment of PF disease, focussing on key findings detectable on plain radiography, ultrasound and magnetic resonance imaging (MRI). Sonographic characteristics of planta...

Hepatitis C-associated osteosclerosis (HCAO) is an uncommon condition characterized by increased bone density, skeletal pain and elevated bone formation markers. Since 1992, only 17 cases have been reported. We herein describe the case of a 61-year-old woman affected by severe pain involving the lower limbs. The laboratory data showed an elevated serum alkaline phosphatase level, and the patien...

Introduction Osteoid osteomas are tumors of the bone which have lower limbs as the commonest site of involvement [1]. These tumors were first described in 1936 by Jaffe [1]. The tumor is described to be osteoblastic and benign [1]. Adoloscent young males are the commonly affected population [1]. The classical presentation is only noted in two-third of the patients [2].Radiographic appearance of...

PURPOSE To determine the nature and extent of regional cortical thinning in patients with mesial temporal lobe epilepsy (MTLE). METHODS High-resolution volumetric MRIs were obtained on 21 patients with MTLE and 21 controls. Mean cortical thickness was measured within regions of interest and point-by-point across the neocortex using cortical reconstruction and parcellation software. RESULTS ...

Bone scan of an 18-year-old male who initially presented with chronic left knee pain showed increased radiotracer uptake in the left knee indicative of osteoarthritis. For the incidental finding of diffusely intense uptake involving the left hemipelvis, Paget’s disease was favored over osteosarcoma and Ewing’s sarcoma. CT scan without IV contrast showed cortical and trabecular thickening of the...

Introdouction: Cone-beam computed tomography (CBCT) scanning is a technological innovation developed in recent years with potential use in oral surgery and many other dental procedures. The aim of this study is to determine the maxillary sinus mucosal thickening in the maxillary premolar-molar area using the CBCT technique. Materials and methods: In this retrospective study, a total of 105 c...