conclusions our study showed that microrelin is as effective as diphereline in reducing psa and testosterone and can be recommended to initiate medical castration in patients with pc. results each group contained 40 patients. in group a, psa was reduced from 75.78 ± 72.43 ng/ml to 1.93 ± 1.40 ng/ml after 6 months and testosterone was reduced from 3.50 ± 1.12 nmol/l to 0.81 ± 0.05 nmol/l. there ...

© 1998 Journals of Reproduction and Fertility 1359-6004/98 $12.50 Steroid hormones play extremely important roles in maintaining bodily homeostasis and reproductive capacity. For example, the adrenal mineralocorticoid aldosterone is essential for maintaining salt balance and, hence, blood pressure, while adrenal glucocorticoids serve to regulate carbohydrate metabolism and also to formulate rea...

treatment of central precocious puberty (cpp) is the administration of gnrh analogs. metabolic syndrome comprised metabolic disturbances that confer increased risk of (cvd) diabetes mellitus (dm) and cardiovascular disease. this study is a longitudinal prospective study in pediatric endocrinology clinic. 30 non-obese children with idiopathic cpp were involved. total body weight, height, blood p...

OBJECTIVE To investigate the incidence and severity of pituitary insufficiency after aneurysmal subarachnoid haemorrhage. METHODS Pituitary function was tested in a series of patients more than 12 months but less than 60 months after aneurysmal subarachnoid haemorrhage using a combined TRH-LHRH-arginine test and the insulin tolerance test, to elucidate possible deficits in the gonadotrophic, ...

Corticotrophin-releasing factor (CRF) is the principal hypothalamic factor governing the pituitary-adrenal axis, but the wide extra-pituitary distribution of CRF and its receptors suggest a major role for this neuropeptide in the integration of the overall physiological and behavioral responses of an organism to stress. We have cloned a CRF receptor complementary DNA (cDNA) by expression in COS...