cox 1

نتایج جستجو برای: cox 1

تعداد نتایج: 2783617 فیلتر نتایج به سال:

Licofelone: A Novel Non-Steriodal Anti-Inflammatory Drug (NSAID) in Arthritis

Journal: Iranian Journal of Pharmacology and Therapeutics 2011

B. Shivakumar, k.m. Manjanna,

Arthritis refers to different medical conditions associated with disorder of the primary structures that determine joint functions such as bones, cartilage and synovial membranes. Drug discovery and delivery to retard the degeneration of joint tissues are challenging. Current treatments of different arthritis involves administration of ideal non-steroidal anti-inflammatory drugs (NSAIDs) but ar...

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Molecular Dynamics Simulations of Arachidonic Acid Complexes with COX-1 and COX-2: Insights into Equilibrium Behavior

Journal: :Biochemistry 2006

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Cyclooxygenase (COX)-1, Cyclooxygenase (COX)-2 and E-cadherin Expression in Colorectal Cancer Patients with Hepatic Metastasis

Journal: :Journal of the Korean Surgical Society 2010

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Correction: Umbelliferone β-d-galactopyranoside exerts an anti-inflammatory effect by attenuating COX-1 and COX-2

Journal: :Toxicology Research 2015

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Codonopsis Decoction Inhibits Aspirin-Induced Gastric Mucosal Injury in Rats by Regulating COX, COX-1, COX-2, TNF-α, IL-6 and TGF-α

Journal: :Biomedical Journal of Scientific & Technical Research 2021

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selective cox-2 inhibitors: a review of their structure-activity relationships

Journal: :iranian journal of pharmaceutical research 0

afshin zarghi department of pharmaceutical chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. sara arfaei department of pharmaceutical chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran.

non-steroidal anti-inflammatory drugs (nsaids) are the competitive inhibitors of cyclooxygenase (cox), the enzyme which mediates the bioconversion of arachidonic acid to inflammatory prostaglandins (pgs). their use is associated with the side effects such as gastrointestinal and renal toxicity. the therapeutic anti-inflammatory action of nsaids is produced by the inhibition of cox-2, while the ...

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