We calculate the dynamics of a nanomechanical oscillator NMO coupled capacitively to a Cooper-pair box CPB by solving a stochastic Schrödinger equation with two Lindblad operators Commun. Math. Phys. 48, 119 1976 . . Both the NMO and the CPB are assumed dissipative, and the coupling is treated within the rotating wave approximation. We show numerically that, if the CPB decay time is smaller tha...

The development of cardiopulmonary bypass (CPB) and open heart surgery in the 1950s has benefited millions of people around the world over the last half century. However, it has been recognized since the beginning that there are detrimental effects to CPB. In an effort to minimize the effects of CPB, a miniaturized CPB (M-CPB) closed circuit system also known as closed circuit extracorporeal ci...

OBJECTIVE Acute kidney injury (AKI) post-cardiac surgery is associated with mortality rates approaching 20%. The development of effective treatments is hindered by the poor homology between rodent models, the mainstay of research into AKI, and that which occurs in humans. This pilot study aims to characterise post-cardiopulmonary bypass (CPB) AKI in an animal model with potentially greater homo...

BACKGROUND Despite improvements in neonatal heart surgery, neurologic complications continue to occur from low-flow cardiopulmonary bypass (LF-CPB) and deep hypothermic circulatory arrest (DHCA). Desflurane confers neuroprotection against ischemia at normothermia and for DHCA. This study compared neurologic outcome of a desflurane-based with a fentanyl-based anesthetic for LF-CPB. METHODS Thi...

BACKGROUND Cardiopulmonary bypass (CPB) is necessary for most cardiac surgery, which may lead to postoperative lung injury. The objective of this paper is to systematically evaluate whether ventilation during CPB would benefit patients undergoing cardiac surgery. METHODS We searched randomized controlled trials (RCTs) through PubMed, Embase, and Cochrane Library from inception to October 2016...

Cardiopulmonary bypass (CPB) is associated with a systemic inflammatory response, which can result in acute lung injury known as "postperfusion syndrome." Neutrophil activation with concomitant serine protease release has been implicated in the pathogenesis of "postperfusion syndrome." Increased plasma levels of neutrophil elastase (NE) have been demonstrated in patients undergoing CPB, and it ...

Cardiopulmonary bypass (CPB) induced systemic inflammation significantly contributes to the development of postoperative complications, including respiratory failure, myocardial, renal and neurological dysfunction and ultimately can lead to failure of multiple organs. Ghrelin is a small endogenous peptide with wide ranging physiological effects on metabolism and cardiovascular regulation. Herei...

Objective: Soluble forms of interleukin-6 (IL-6) receptors are known to modulate biological activities of IL-6. The purpose of the study was to measure circulating levels of IL-6, sIL-6R and sgp130 in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass (CPB group) or without CPB (non-CPB group). Methods: The CPB group included 19 patients and the non-CPB group 12 pat...

some factors affecting crude protein balance (cpb), as a measure of efficiency, were studied using 2824 records of 501 lactating holstein cows. the cpb (kg d-1) was calculated as crude protein (cp) intake (kg) minus cp yield (kg). two different statistical methods including principal components (pcs) and general linear model analyses were used to study the effects of different factors. crude pr...

High mobility group box 1 (HMGB1), which has properties similar to those of proinflammatory cytokines, is released from activated immune cells and necrotic cells. It is known that cardiopulmonary bypass (CPB) induces systemic inflammation and aortic cross-clamping induces myocardial ischemia. This study was conducted to clarify whether HMGB1 is released in CPB-supported cardiac surgery in compa...