OBJECTIVE To examine the efficacy of 2 over-the-counter cosmeceutical creams in reducing facial rhytids-Freeze 24/7 Anti-Wrinkle Cream (Freeze 24/7 International LLC, New York, New York) and LiftFusion Micro-Injected M-Tox Transdermal Face Lift (Fusionbeauty, Inc, Boca Raton, Florida)-against placebo (Nutraderm Therapeutic Lotion; Healthpoint, Inc, San Antonio, Texas). METHODS A prospective, ...

BACKGROUND Occupational skin contact with lipophilic substances is a risk factor for the development of irritant hand dermatitis. Skin protection creams form part of the personal protective equipment, and some are claimed to protect against lipophilic irritants. However, their benefit against solvents is under debate. OBJECTIVES To evaluate the efficacy of barrier creams claimed to protect ag...

Background. Skin infections occur commonly and often present therapeutic challenges to practitioners due to the growing concerns regarding multidrug-resistant bacterial, viral, and fungal strains. The antimicrobial properties of zinc sulfate and copper sulfate are well known and have been investigated for many years. However, the synergistic activity between these two metal ions as antimicrobia...

The purpose of this study is to elucidate the physical properties of various commercially available topical corticosteroid preparations. We compared comfort after application and the physical properties affecting topical application among brands of commercially available topical corticosteroid ointments and creams to identify factors affecting quality of life after application. We investigated ...

Topiceuticals can be defined as specialized pharmaceutical formulations containing topically applied drugs. Topiceutical analgesics need to be differentiated from transdermal formulations of analgesics. The latter formulations are specially designed for the active pharmaceutical ingredient to penetrate all skin structures and to generate measurable plasma levels of the formulated analgesic, suc...

A moisturizing cream mixed with a steroid ointment is frequently prescribed to patients suffering from atopic dermatitis. However, there is a concern that the mixing operation causes destabilization. The present study was performed to investigate the stability of such preparations closely using magnetic resonance imaging (MRI). As sample preparations, five commercial moisturizing creams that ar...

Background. We compared the efficacy of P. granatum (P) flower extract with that of silver sulfadiazine (SSD) for treating thermal burn injuries in rats. Methods. Ten Wistar rats in each group were topically given base cream, normal saline, cream containing 1% SSD, or creams containing 5% or 10% Punica granatum flower extract. The treatments were administered once daily until complete wound hea...