more than eighty percent of patients with coronary heart diseases (chd) have conventional risk factors. prevalence of well known risk factors seems to show a different pattern in younger patients and individual above 55 years. to evaluate the pattern of conventional chd risk factors in healthy individuals in two different age groups. a large scale population based survey of 31999 individuals fr...

results during the 3 months study, in the placebo group, systolic bp (sbp) increased with 6.3 mmhg and diastolic bp (dbp) increased with 4.6 mmhg, changes which were significant. after the 3 months, the effect of garlic on sbp, after adjusting for baseline value, was significant, and this effect was more significant in hypertensive patients. plasma lipids and lipoproteins did not change signific...

background: coronary angiography, albeit a safe procedure, may cause serious complications especially in patients with left main stenosis (lms). this study was designed to investigate the efficacy of workload achieved by exercise tolerance test (ett) in predicting lms in candidates for coronary angiography. methods: a total of 743 patients with a positive ett who subsequently underwent cardiac ...

background: c linical trials of revascularization have routinely under-enrolled elderly subjects. thus, symptom relief and improved survival might not apply to elderly patients, in whom the risk of mortality and disability from revascularization procedures seems to be high and co-morbidity is more prevalent. the present case control study was performed to draw a comparison in terms of the proce...

conclusions the pattern and number of vessels involved were similar in both groups. based on common prevalence of traditional risk factors among two groups, planning for lifestyle changes is recommended. results of the 112 patients, 51 (45.5%) were in group a and 61 (54.5%) were in group b with mean age of 37.6 ± 4.4 and 63 ± 8.5, respectively. no significant statistical differences were found ...

conclusions the scf phenomenon is relatively frequent, particularly among patients with acute coronary syndrome who are scheduled for coronary angiography. hypertension, a low hdl-c level, and high hemoglobin level can be considered independent predictors of this phenomenon. results among the 3600 patients scheduled for selective coronary angiography, 75 (2%) met the scf criteria. scf and neca ...

background abnormalities in the velocity and pattern of myocardial shortening on tissue doppler imaging (tdi) have been proposed to aid in the noninvasive diagnosis of coronary artery disease (cad). objectives we investigated the diagnostic value of post-systolic shortening (pss), a delayed ejection velocity of the myocardium after the closure of the aortic valve, on tdi in the diagnosis of cad...

conclusions our findings revealed that the severity of coronary artery stenosis is common in diabetic patients compared to nondiabetics. early diagnosis and treatment of cad in diabetic patients is recommended. results based on data found in our study, 93.8% of diabetic and 83.4% of nondiabetic patients were shown to suffer coronary artery stenosis. severe involvement (grade 3vd) of coronary ar...

background coronary artery disease (cad) is the most common cause of death worldwide. mef2a directly regulates target genes in the process of muscle development. this gene product is a transcription factor. mef2a protein in homodimer or heterodimer forms binds to a/t-rich cis elements with conserved sequence in promoter, regulator, and enhancer of many genes, which are determining in evolution ...