We measured human immunodeficiency virus (HIV) ribonucleic acid (RNA) in paired cerebrospinal fluid (CSF) and plasma samples in a prospective study of 91 HIV-infected, antiretroviral therapy-naive patients with cryptococcal meningitis. Cerebrospinal fluid HIV RNA was lower than in plasma (median 4.7 vs 5.2 log10 copies/mL, P < .0001) and positively correlated with plasma HIV RNA, peripheral CD4...

article: Cryptococcal-related meningoencephalitis in a patient with sarcoidosis and CD4 lymphocytopenia: thorough immunological characterization of lymphocyte homeostasis - Journal Neurosurgical Sciences 2021 April;65(2):207-10 Minerva Medica Journals

also reported in their series of 25 HIV-positive patients presenting with proteinuria, 2 patients with cryptococcal renal infiltration. The patient described in the case report had evidence of macroalbuminuria and tubular dysfunction as evidenced by significant urinary sodium loss on the 24-h urine specimen. This may be attributable to both glomerular and tubulo-interstitial cryptococcal invasi...

Cryptococcal pneumonia usually occurs in immunocompromised patients with malignancy, acquired immune deficiency syndrome, organ transplantations, immunosuppressive chemotherapies, catheter insertion, or dialysis. It can be diagnosed by gaining tissues in lung parenchyma or detecting antigen in blood or bronchoalveolar lavage fluid. Here we report an immunocompetent 32-year-old male patient with...

We herein report the case of a 72-year-old-man with pulmonary cryptococcoma along with cryptococcal meningitis who underwent surgery for pulmonary lesions while receiving chemotherapy. We noted two major clinical issues. First, the presence of pulmonary cryptococcoma had a detrimental influence on the cryptococcal meningitis. Second, resolution of the pulmonary cryptococcoma through antifungal ...

Immune reconstitution inflammatory syndrome (IRIS) presents as an exaggerated immune reaction that occurs during dysregulated restoration in immunocompromised patients late-stage human immunodeficiency virus (HIV) infection who have commenced antiretroviral treatments (ART). Virtually any opportunistic pathogen can provoke this type of disorder. In review, we focus on recent developments the id...

conclusions symptomatic hyponatremia secondary to siadh remains a rare complication of cryptococcal meningitis. case presentation a 67-year-old male with liver transplantation due to hepatitis c (hcv) related liver cirrhosis developed severe hyponatremia four months after liver transplantation, which was discovered during routine clinic visit. patient was referred to the emergency department, t...