Pantothenate kinase is an essential enzyme in the bacterial life cycle. It catalyzes the phosphorylation of pantothenate (vitamin B5) to 4'-phosphopantothenate, the first step in the coenzyme A biosynthetic pathway. The enzyme from Mycobacterium tuberculosis, MW 35.7 kDa, has been cloned, expressed, purified and crystallized in two different trigonal crystal forms, both belonging to space group...

Sso6206, a 10.5 kDa protein from Sulfolobus solfataricus, has been overexpressed, purified and crystallized. The protein crystallizes in space group P6(1/5)22, with unit-cell parameters a = b = 157.8, c = 307.3 A. The crystals are hexagonal bipyramids and a data set has been collected to 2.4 A resolution. Molecular replacement cannot be attempted as no convincing model can be identified. Crysta...

ticl4, ammonia, inorganic salts as raw material, nanometer composite-crystal tio2 powders were synthesized by two-step chemical method. precursors were crystallized with different phase and stable composite-crystal tio2 with anatase and rutile phase was prepared at low temperature. quantitative control of crystal phase was realized. remarkable factors including reaction ph value, reaction time,...

Chemokines are chemotactic cytokines comprised of 70-100 amino acids. The chemokines CXCL12 and CCL5 are the endogenous ligands of the CXCR4 and CCR5 G protein-coupled receptors that are also HIV co-receptors. Biochemical, structural and functional studies of receptors are ligand-consuming and the cost of commercial chemokines hinders their use in such studies. Here, we describe methods for the...

The preparation of novel nitrilium derivatives closo-dodecaborate anion [B12H11NCR]−, R = n-C3H7, i-C3H7, 4-C6H4CH3, 1-C10H7 is described. Target compounds were obtained in good yields (up to 73%). synthesis target borylated was characterised by the simplicity chemical apparatus and absence necessity for purification desired compounds. crystal structures previously [B12H11NCCH3]− [B12H11NCC3H7]...

: optical separate spatial dark and bright soliton pairs in steady-state case in one dimension, for a series circuit consisting of two-photon photorefractive (pr) crystal are investigated. each crystal can be supported the spatial soliton, and at least one must be photovoltaic. the two solitons are known collectively as separate spatial soliton pairs with dark–dark, bright–dark and bright–brigh...