The present study investigated whether reactivity to nicotine-related cues would attenuate across four experimental sessions held 1 week apart. Participants were nineteen non-treatment seeking, nicotine-dependent males. Cue reactivity sessions were performed in an outpatient research center using in vivo cues consisting of standardized smoking-related paraphernalia (e.g., cigarettes) and neutra...

Cocaine addiction is increasingly considered to stem from the development of maladaptive, stimulus bound, drug seeking habits that both contribute to the maintenance of drug use despite aversive consequences, and also to high rates of relapse. However because relapse by definition occurs only after a period of abstinence, the relative contribution of habits and pharmacological withdrawal from t...

Cocaine addiction is increasingly considered to stem from the development of maladaptive, stimulus bound, drug seeking habits that both contribute to the maintenance of drug use despite aversive consequences, and also to high rates of relapse. However because relapse by definition occurs only after a period of abstinence, the relative contribution of habits and pharmacological withdrawal from t...

Potassium hexaniobate nanoscrolls (NS-K4Nb6O17) formed by exfoliation of lamellar K4Nb6O17 were studied as building blocks for visible-light-driven H2 production (λ > 420 nm) from water using tris(2,2′bipyridyl)ruthenium(II) chloride (Ru(bpy)3) as a sensitizer and ethylenediaminetetraacetic acid (EDTA) as an electron donor. The surface of NS-K4Nb6O17 is negatively charged at pH 3-11, enabling c...

Arteries are lined by endothelial cells and are wrapped by one or more layers of smooth muscle (SM) cells. There are electrical coupling and chemical signaling between SM cells and between SM cells and endothelial cells, and SM cells receive numerous neurotransmitter, endocrine, and paracrine signals that promote either contraction or relaxation. Independently of these signals, arterial SM cell...

Randomized placebo-controlled trial to evaluate chronic dosing effects of propranolol in asthma 4 Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma 4 Use of continuous positive airway pressure reduces airway reactivity in adults with asthma 5 A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma 5 Cyclooxygenase-2 inhibi...

Citation: Seiffert-Sinha K, Khan S, Attwood K, Gerlach JA and Sinha AA (2018) Anti-Thyroid Peroxidase Reactivity Is Heightened in Pemphigus Vulgaris and Is Driven by Human Leukocyte Antigen Status and the Absence of Desmoglein Reactivity. Front. Immunol. 9:625. doi: 10.3389/fimmu.2018.00625 anti-Thyroid Peroxidase reactivity is heightened in Pemphigus Vulgaris and is Driven by human leukocyte a...

Reactivity to smoking-related cues may be an important factor that precipitates relapse in smokers who are trying to quit. The neurobiology of smoking cue reactivity has been investigated in several fMRI studies. We combined the results of these studies using activation likelihood estimation, a meta-analytic technique for fMRI data. Results of the meta-analysis indicated that smoking cues relia...