Driven by global competition and rising cost pressure in the pharmaceutical industry, over the last ten years single-use bioreactors have been increasingly used for animal cell cultivations in screening experiments, seed inoculum and seed train productions as well as in small and medium scale production processes of proteins (in particular, antibodies and vaccines). In contrast to re-usable bio...

I examine key SDI concepts: ‘information’, ‘decision processes’, ‘people’, ‘management systems’, ‘social structure’ and ‘information technology’. I attempt to make explicit commonly held assumptions about the nature of these concepts, the ways they contribute to a ‘construction’ view of SDI implementation and their apparent disconnectedness with the realities in the developing world. I suggest ...

Despite the high potential as feedstock for the production of fuels and chemicals, the industrial cultivation of microalgae still exhibits many issues. Yield in microalgae cultivation systems is limited by the solar energy that can be harvested. The availability of reliable models representing key phenomena affecting algae growth may help designing and optimizing effective production systems at...

When building soil organic matter (SOM) contents in agricultural production systems, stabilization of both pre-existing as well as added C is important. A laboratory mineralization experiment was conducted over 374 days to evaluate the effect of pre-existing SOM on soil C mineralization after addition of organic matter (OM) using sugar cane. The SOM gradient used here stretched from 21 to 106 g...