Previous experimental studies suggest that bile salt-induced colonic fluid secretion is mediated by adenosine 3':5'-phosphate (cyclic AMP). Two biopsy specimens of colonic mucosa were obtained endoscopically before and after different periods of therapy (five, 10, or 15 days), from each of 21 patients receiving chenodeoxycholic acid. A rise of cyclic AMP intracellular levels was found, but only...

The effect of phototherapy on plasma cyclic-AMP in newborn infants has been studied. Our results suggest that phototherapy does not produce appreciable changes in plasma cyclic-AMP levels.

The ingestion of particles by phagocytizing cells is accompanied by marked changes in such metabolic parameters as oxygen consumption, glycolysis, glycogenolysis, H202 production, and activity of the hexose-monophosphate shunt, with the extent of these events depending on the particular cell type studied (for references see 1, 4, 6, 7) . In general, these metabolic changes can be observed withi...

During growth of myxamoebae of Dictyostelium discoideum (strain Ax-2) in axenic medium, the myxamoebae secrete cyclic AMP. As the cells leave the exponential phase of growth and enter the stationary phase, there is an approximate doubling of the intracellular cyclicAMP content, but the amount ofextracellular cyclicAMP remains proportional, at all times, to the number ofmyxamoebae present. Durin...

a bstract background: recent attempts have been focused on employing chemical and natural supplemental agents for treatment of cyclic mastalgia. among various agents, the potential effects of vitamins remain questionable. in the present study, we examined the efficacy of two types of these vitamin supplements (vitamin e and vitamin b6) in improving pain severity in cyclic mastalgia.   materials...

Addition of 1-3 mM-8-bromo-cyclic AMP to monolayer cultures of H-4 rat hepatoma cells resulted in a rapid but short-lived increase in tyrosine aminotransferase (EC 2.6.1.5) activity. The transient nature of this induction is due to desensitization to 8-bromo-cyclic AMP. Throughout this time course of induction and desensitization, removal of 8-bromo-cyclic AMP resulted in a rapid and significan...

We have studied cyclic adenosine 3',5'-monophosphate (cyclic AMP) concentrations in human peripheral blood lymphocytes after stimulation with phytohemagglutinin (PHA), isoproterenol, prostaglandins, and aminophylline. Purified lymphocytes were obtained by nylon fiber chromatography, and low speed centrifugation to remove platelets. Cyclic AMP levels were determined by a highly sensitive radioim...

The 4-chlorophenylthio analogue of cyclic AMP evoked profound and long-lasting changes in cytosolic [Ca2+] ([Ca2+]i) in pituitary-derived GH3 cells. However, vasoactive intestinal peptide (VIP), a hormone considered to act via cyclic AMP, was ineffective in modulating [Ca2+]i. The ability of VIP to modulate [Ca2+]i was enhanced by treatments that increased intracellular cyclic AMP. Much greater...

In this paper we introduce the definition of transitivity for oriented $3$--hypergraphs in order to study partial and complete cyclic orders. This definition allow us to give sufficient conditions on a partial cyclic order to be totally extendable. Furthermore, we introduce the $3$-hypergraph associated to a cyclic permutation and characterize it in terms of cyclic comparability $3$-hypergraphs...

in this study, a researching program is conducted by cyclic triaxial test to determine the post-cyclic behavior of bushehr carbonate sand retrieved from the north of the persian gulf, under anisotropic consolidation at 200 kpa confining pressure. the article compares the post-cyclic monotonic strength and excess pore water pressures generated after the test with the pre-cyclic monotonic results...