T HE syndrome of chronic neutropenia has long been recognized. Roberts and Kracke’ in 1931 described the symptom complex of fatigability, weakness, nervousness, and a predisposition to intercurrent infections which occurred in a large percentage of their patients who had neutropenia. Doan2 classified the chronic neutropenias in three groups: (i) those cases with a persiste itly low leukocyte co...

Chronic neutropenia (CN) is a rare disorder in children. It is defined by an absolute neutrophil count (ANC) below 1500 cells per cubic microliter of peripheral blood, lasting for at least 6 months. It can be acquired or congenital. More frequent – acquired chronic neutropenia is mainly caused by: malnutrition, exposure to drugs, chemical compounds and viral infections. CN is the cardinal sympt...