نتایج جستجو برای: cyclooxygenase

تعداد نتایج: 15217  

Journal: :The Journal of clinical investigation 1978
J W Burch N Stanford P W Majerus

Aspirin inhibits platelet function by permanently acetylating the cyclooxygenase that forms prostaglandins. We determined the sensitivity of platelets to aspirin in normal subjects by measuring [3H-acetyl]aspirin-susceptible cyclooxygenase in washed platelets obtained at various times after aspirin ingestion. A single 325-mg aspirin dose inactivated 89% of platelet cyclooxygenase. The inhibitio...

Aspirin eugenol ester (AEE) is a promising drug candidate, which is used for the treatment of inflammation, pain and fever and the prevention of cardiovascular diseases. This study focuses on the effect of AEE on five proteins which are related to inflammation and thrombosis, including cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), C-reactive protein (CRP), prothrombin (FII) and arachidona...

Journal: :Drug Discovery Today: Therapeutic Strategies 2008

Journal: :Proceedings of the National Academy of Sciences 1992

Journal: :Canadian Medical Association Journal 2006

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