AIM We aim to evaluate the National Cancer Institute (NCI) treatment protocol and its outcome regarding recurrence, progression and survival in patients with T1G3 urinary bladder transitional cell carcinoma. PATIENTS AND METHODS In a retrospective study, between January 2001 and December 2007, all 34 patients with T1G3 bladder transitional cell carcinoma (TCC), after complete transurethral re...

BACKGROUND The benefit of pelvic lymphadenectomy in patients with cancer of the urinary bladder remains controversial. Though the inclusion of lymph node dissection in conjunction with radical cystectomy for patients with clinically negative nodes is well accepted, however, the extent of the nodal dissection remains contentious, particularly in patients with gross disease and T1G3 cancer. The e...

BACKGROUND Several non-randomised trials have shown that transitional-cell carcinoma of the bladder is a moderately chemosensitive tumour. We investigated whether the addition of neoadjuvant cisplatin-based chemotherapy to radical surgery or radiotherapy would improve survival. METHODS Patients with T2 G3, T3, T4a, N0-NX, or M0 transitional-cell carcinoma of the bladder undergoing curative cy...

INTRODUCTION Different sexual function-preserving surgical techniques aimed at improving voiding and sexual function in patients undergoing radical cystectomy for bladder cancer have been described. The objective of this systematic review is to determine the effect of sexual function-preserving cystectomy (SPC) on functional and oncological outcomes. MATERIALS AND METHODS Relevant databases w...

© The Canadian Journal of UrologyTM; 20(4); August 2013 Address correspondence to Dr. Daniel J. Canter, Einstein Health Network, 60 E. Township Line Road, Elkins Park, PA 19027 USA Balancing disease and risk in octogenarians undergoing radical cystectomy Ronak Gor, DO,1 Daniel J. Canter, MD1,2 1Einstein Health Network, Philadelphia, Pennsylvania, USA 2Urologic Institute of Southeastern Pennsylv...

PURPOSE Currently objective perioperative risk assessment metrics are lacking for radical cystectomy. Using a simple 10-point scale similar to neonatal Apgar assessment we evaluated whether a surgical outcome score calculated immediately after radical cystectomy would predict major complications and mortality. MATERIALS AND METHODS We identified 155 consecutive radical cystectomies performed ...