نتایج جستجو برای: cystein
تعداد نتایج: 282 فیلتر نتایج به سال:
Drosophila is a well-established model to study the molecular basis of neurodegenerative diseases. We carried out a misexpression screen to identify genes involved in neurodegeneration examining locomotor behavior in young and aged flies. We hypothesized that a progressive loss of rhythmic activity could reveal novel genes involved in neurodegenerative mechanisms. One of the interesting candida...
All the members of the triosephosphate isomerase (TIM) family possess a cystein residue (Cys126) located near the catalytically essential Glu165. The evolutionarily conserved Cys126, however, does not seem to play a significant role in the catalytic activity. On the other hand, substitution of this residue by other amino acid residues destabilizes the dimeric enzyme, especially when Cys is repl...
Sự dimer protein đóng vai trong quan trọng hầu hết các hoạt động sinh học tế bào như: enzyme, thụ thể màn, nhân tố truyền tín hiệu phiên mã. Do đó, kiểm soát sự của giúp được quá trình này. Trong nghiên cứu này, phân tử Curcubit[8]uril sử dụng để có chứ đuôi FCG (phenylalanine-cystein-glycine) ở đầu N (N-terminus) protein. Cặp chỉ thị CFP/YFP (cyan fluorescent protein/yellow protein) chứa dung ...
Background: Hypothyroidism is characterized by a decline in basal metabolic rate which can lead to glycogen build up and decreased enzyme activity energy synthesis other regulatory systems. Thyroid hormones have number of key targets including skeletal muscle. Thus, hypothyroid patients altered glycolysis, glycogenolysis mitochondrial metabolism an impact on muscle function. Timely assessment b...
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