نتایج جستجو برای: cytome assay

تعداد نتایج: 221732  

2012
Maïté Hanot Anthony Boivin Céline Malésys Michaël Beuve Anthony Colliaux Nicolas Foray Thierry Douki Dominique Ardail Claire Rodriguez-Lafrasse

Poor local control and tumor escape are of major concern in head-and-neck cancers treated by conventional radiotherapy or hadrontherapy. Reduced glutathione (GSH) is suspected of playing an important role in mechanisms leading to radioresistance, and its depletion should enable oxidative stress insult, thereby modifying the nature of DNA lesions and the subsequent chromosomal changes that poten...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد علوم دارویی - دانشکده داروسازی 1394

چکیده: هدف اصلی اندازه گیری و مقایسه میزان قدرت مهارکنندگی عصاره ها و فراکشن های پلار دو گیاه phlomis rigida و phlomis kurdica بر روی آنزیم تیروزیناز به روش assay mushroom tyrosinase به منظور دستیابی به منابع طبیعی جدید جهت درمان اختلالات ناشی از هایپرپیگمانتاسیون. اهداف فرعی الف) تعیین و مقایسه میزان توتال فنول موجود در عصاره ها و فراکشن های پلار بدست آمده از دو روش عصاره گیری به روش fol...

H. Mozdarani, M. Salimi,

It is now universally accepted that DNA is the main target for damages caused by physical and chemical genotoxicants. Although there are different methods to measure directly the induced DNA damages but due to fast repair processes in cellular environment, most of the damages would be repaired even before sampling, therefore processed DNA damages, i.e. damages left unrepaired after acting repai...

Journal: :Cancer prevention research 2014
Caroline F Bull Graham Mayrhofer Nathan J O'Callaghan Amy Y Au Hilda A Pickett Grace Kah Mun Low Dimphy Zeegers M Prakash Hande Michael F Fenech

The essential role of dietary micronutrients for genome stability is well documented, yet the effect of folate deficiency or excess on telomeres is not known. Accordingly, human WIL2-NS cells were maintained in medium containing 30, 300, or 3,000 nmol/L folic acid (FA) for 42 days to test the hypothesis that chronic folate deficiency would cause telomere shortening and dysfunction. After 14 day...

Journal: :iranian journal of public health 0
s.y. seyedna ; m. sheidai

testosterone level was determined in six different populations of iran using saliva steroid assay. significant difference was observed in morning and afternoon testosterone level of the same individual (p>0.00l) significant difference was also noticed among different regions studied (p>0.00 1). comparisons between alcoholics and nonalcoholic as well as smokers and nonsmokers showed significant ...

Journal: :Arhiv za higijenu rada i toksikologiju 2015
Mirta Milić Ružica Rozgaj Vilena Kašuba Ana-Marija Jazbec Boris Starčević Barnaba Lyzbicki Gloria Ravegnini Corrado Zenesini Muriel Musti Patrizia Hrelia Sabrina Angelini

Individual sensitivity to ionising radiation (IR) is the result of interaction between exposure, DNA damage, and its repair, which is why polymorphisms in DNA repair genes could play an important role. We examined the association between DNA damage, expressed as micronuclei (MNi), nuclear buds (NBs), and nucleoplasmic bridges (NPBs) and single nucleotide polymorphisms in selected DNA repair gen...

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