The aim was to test the effects of aminophylline (AP) on pbl'1!nlcotomlud rats. Fifty seven male rats of tbe Wlstar AllllCSilrtellzed with 1.3 g·kg• urethane l.p. They were pbrentCorrespondence: Dr. F. Palel:ek, Institute of Pathophysiology FDL: Ke Karloon 4, 12000 PRAHA Czechoslovakia. lnto 6 groups and given 5, 10, 20, 40 and 80 mg· kg-• AP dlng volume of saUoe. Ventilation, tracheal occlusio...