INTRODUCTION .......................................................................................... 258 I. THE EVOLUTION OF PRODUCTS LIABILITY LAW ...................... 262 A. Early American Law ....................................................... 263 B. Modern American Law ................................................... 265 C. The Liability “Crisis” ...................................

The Ryukyu five-lined skink (Plestiodon marginatus) is an island lizard that is even found in tiny islets with less than half a hectare of habitat area. We hypothesized that the island populations are maintained under frequent gene flow among the islands or independent of each other. To test our hypotheses, we investigated genetic structure of 21 populations from 11 land-bridge islands that wer...

Viruses are the major cause of lower respiratory tract infections in childhood and the main viruses involved are Human Respiratory Syncytial Virus (HRSV), Human Metapneumovirus (HMPV), Influenzavirus A and B (FLUA and FLUB), Human Parainfluenza Virus 1, 2 and 3 (HPIV1, 2 and 3) and Human Rhinovirus (HRV). The purposes of this study were to detect respiratory viruses in hospitalized children you...

24 W. Lin, D.S. Lawrence, J. Org. Chem. 2002, 67, 2723–2726. 25 H.J. Montgomery, B. Perdicakis, D. Fishlock, G.A. Lajoie, E. Jervis, J.G. Guillemette, Bioorg. Med. Chem. 2002, 10, 1919–1927. 26 M. Lu, O.D. Fedoryak, B.R. Moister, T.M. Dore, Org. Lett. 2003, 5, 2119– 2122. 27 V.G. Robu, E.S. Pfeiffer, S.L. Robia, R.C. Balijepalli, Y. Pi, T. J. Kamp, J.W. Walker, J. Biol. Chem. 2003, 278, 48154–4...

To the Editor: Dermacentor spp. ticks are found in many countries in Europe, and are vectors for several pathogens, including Francisella tularensis, Coxiella burnetii, Rickettsia spp., and Babesia canis (1,2). Because Dermacentor marginatus ticks require warm dry habitats, these ticks are found in only a few areas in southern Germany, mainly in the Rhine and Main valleys (3). However, these ti...

Terung (Solanum melongena) merupakan tanaman sayur-sayuran dari famili Solanaceae yang dapat ditemukan tumbuh di daerah tropik maupun subtropik. P. marginatus hama polipag menyerang terung. Penelitian ini bertujuan untuk mempelajari beberapa aspek biologi kutu putih (P. marginatus) pada serangga (Paracoccus dilaksanakan rumah kaca dan laboratorium Hama Tumbuhan, Fakultas Pertanian, Universitas ...

Previous studies have indicated that human immunodeficiency virus type 1 (HIV-1) protease inhibitors (PIs) are less active at blocking viral replication in HIV-1 infected peripheral blood monocytes/macrophages (M/M) than in HIV-1-infected T cells. We explored the hypothesis that oxidative modification and/or metabolism of the PIs in M/M might account for this reduced potency. We first tested th...

KNI-272 is a human immunodeficiency virus (HIV) protease inhibitor with potent activity in vitro. We studied the pharmacokinetics of KNI-272 in the plasma and cerebrospinal fluid (CSF) of a nonhuman primate model and after intravenous and oral administration to children with HIV infection. Plasma and CSF were sampled over 24 h after the administration of an intravenous dose of 50 mg of KNI-272 ...