نتایج جستجو برای: d1b

تعداد نتایج: 147  

Journal: :Plant Breeding 2023

Fusarium head blight (FHB) resistance in wheat and triticale has a high priority the European Union because of strict guidelines for major mycotoxins deoxynivalenol (DON) zearalenone (ZON) admission policy regulatory authorities. Potentially 70% arable land Germany about 60% Austria can be affected by Fusarium. Although epidemics occur only some years and/or regions, DON ZON are detected every ...

Journal: :BMC Plant Biology 2021

Abstract Background The overall genetic distribution and divergence of cloned genes among bread wheat varieties that have occurred during the breeding process over past few decades in Ningxia Province, China, are poorly understood. Here, we report diversities 44 important related to grain yield, quality, adaptation resistance 121 86 introduced cultivars advanced lines. Results population struct...

Journal: :Environmental and Experimental Botany 2022

Genotype-environment interaction (GxE) has a great impact on wheat physiology, morphology and grain yield (GY). We evaluated an association mapping panel of spring advanced lines for chlorophyll content, canopy temperature (CT), yield-related traits under three different watering regimes in two consecutive growing seasons. Genome-wide identified 457 SNPs, with significant effects that varied th...

Journal: :Minerals 2021

Multiscale structural analysis is carried out to explore the sequence of superposed pre-Alpine chloritoid–staurolite–andalusite metamorphic assemblages in polydeformed Variscan basement upper Val Camonica, central Southalpine domain. The dominant fabric Camonica late-Variscan S2 foliation, marked by greenschist facies minerals and truncated base Permian siliciclastic sequences. intersection wit...

Journal: :Current issues in molecular biology 2009
U B Karangula M A Kassem L Gupta H A El-Shemy D A Lightfoot

In soybean (Glycine max L. Merr.) combining resistance to cyst nematode (SCN; Heterodera glycines I.) with high seed yield remains problematic. Molecular markers linked to quantitative trait loci (QTL) have not provided a solution. Sets of markers describing a collection of favorable alleles (linkats) may assist plant breeders seeking to combine both traits. The objective of this analysis was t...

2010
Xuanmao Jiao Chenguang Wang L. Andrew Shirley Hany Elsaleh Olav Dahl Evi Soutoglou Erik S. Knudsen Richard G. Pestell

nloaded DNA damage response (DDR) activates downstream pathways including cell cycle checkpoints. The D1 gene is overexpressed or amplified in many human cancers and is required for gastrointestinal, , and skin tumors in murine models. A common polymorphism in the human cyclin D1 gene is atively spliced, resulting in cyclin D1a and D1b proteins that differ in their carboxyl terminus. Cyclin ere...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1996
E Mezey G Eisenhofer G Harta S Hansson L Gould B Hunyady B J Hoffman

Cells of the exocrine pancreas produce digestive enzymes potentially harmful to the intestinal mucosa. Dopamine has been reported to protect against mucosal injury. In looking for the source of dopamine in the small intestine, we found that the duodenal juice contains high levels of dopamine and that the pancreas itself has a high dopamine [and dihydroxyphenylalanine (dopa)] content that does n...

2010
Xuanmao Jiao Chenguang Wang L. Andrew Shirley Hany Elsaleh Olav Dahl Evi Soutoglou Erik S. Knudsen Richard G. Pestell

Downlo DNA damage response (DDR) activates downstream pathways including cell cycle checkpoints. The D1 gene is overexpressed or amplified in many human cancers and is required for gastrointestinal, , and skin tumors in murine models. A common polymorphism in the human cyclin D1 gene is atively spliced, resulting in cyclin D1a and D1b proteins that differ in their carboxyl terminus. Cyclin erex...

Journal: :Blood 2007
Adrian Wiestner Mahsa Tehrani Michael Chiorazzi George Wright Federica Gibellini Kazutaka Nakayama Hui Liu Andreas Rosenwald H Konrad Muller-Hermelink German Ott Wing C Chan Timothy C Greiner Dennis D Weisenburger Julie Vose James O Armitage Randy D Gascoyne Joseph M Connors Elias Campo Emilio Montserrat Francesc Bosch Erlend B Smeland Stein Kvaloy Harald Holte Jan Delabie Richard I Fisher Thomas M Grogan Thomas P Miller Wyndham H Wilson Elaine S Jaffe Louis M Staudt

A gene expression signature of tumor proliferation rate in mantle cell lymphoma (MCL) is an overriding molecular predictor of the length of survival following diagnosis. Many strongly proliferative MCL tumors have exceptionally high cyclin D1 mRNA levels and preferentially express short cyclin D1 mRNA isoforms. We demonstrate here that these short mRNAs are cyclin D1a isoforms with truncated 3'...

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