نتایج جستجو برای: dcc of tseand tsui

تعداد نتایج: 21164334  

2014
Christian M. Hafner Michael McAleer Gian Piero Aielli Massimiliano Caporin Guillaume Gaetan Martinet

One of the most widely-used multivariate conditional volatility models is the dynamic conditional correlation (or DCC) specification. However, the underlying stochastic process to derive DCC has not yet been established, which has made problematic the derivation of asymptotic properties of the Quasi-Maximum Likelihood Estimators (QMLE). To date, the statistical properties of the QMLE of the DCC...

Journal: :Cell reports 2013
Katherine E Horn Stephen D Glasgow Delphine Gobert Sarah-Jane Bull Tamarah Luk Jacklyn Girgis Marie-Eve Tremblay Danielle McEachern Jean-François Bouchard Michael Haber Edith Hamel Paul Krimpenfort Keith K Murai Anton Berns Guy Doucet C Andrew Chapman Edward S Ruthazer Timothy E Kennedy

The transmembrane protein deleted in colorectal cancer (DCC) and its ligand, netrin-1, regulate synaptogenesis during development, but their function in the mature central nervous system is unknown. Given that DCC promotes cell-cell adhesion, is expressed by neurons, and activates proteins that signal at synapses, we hypothesized that DCC expression by neurons regulates synaptic function and pl...

Journal: :Current Biology 2009
Josep Call Claudio Tennie

(Figure 1A,B). These results illustrate that DCC distribution is dynamically specified by developmental changes in gene expression. The aspect of transcriptional activity recognized by the DCC is unknown. Possibilities include chromatin features (e.g., nucleosome-free regions or variants and modifications of histones), or the transcription machinery itself. One suspect is histone H3 K4 methylat...

2017

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene was identified in 1989 by geneticist Lap-Chee Tsui and his research team as the gene associated with cystic fibrosis [4] (CF). Tsui?s research pinpointed the gene, some mutations to which cause CF, and it revealed the underlying disease mechanism. The CFTR gene encodes a protein in cell membranes in epithelial tissues and affec...

2018

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene was identified in 1989 by geneticist Lap-Chee Tsui and his research team as the gene associated with cystic fibrosis [4] (CF). Tsui?s research pinpointed the gene, some mutations to which cause CF, and it revealed the underlying disease mechanism. The CFTR gene encodes a protein in cell membranes in epithelial tissues and affec...

2011
Andrew A. Jarjour Margaret Durko Tamarah L. Luk Nathalie Marçal Masoud Shekarabi Timothy E. Kennedy

Deregulation of mechanisms that control cell motility plays a key role in tumor progression by promoting tumor cell dissemination. Secreted netrins and their receptors, Deleted in Colorectal Cancer (DCC), neogenin, and the UNC5 homologues, regulate cell and axon migration, cell adhesion, and tissue morphogenesis. Netrin and netrin receptor expression have previously been shown to be disrupted i...

2016
Hans-Juergen Schulten Deema Hussein Fatima Al-Adwani Sajjad Karim Jaudah Al-Maghrabi Mona Al-Sharif Awatif Jamal Fahad Al-Ghamdi Saleh S. Baeesa Mohammed Bangash Adeel Chaudhary Mohammed Al-Qahtani

Meningiomas are the most common primary brain tumors bearing in a minority of cases an aggressive phenotype. Although meningiomas are stratified according to their histology and clinical behavior, the underlying molecular genetics predicting aggressiveness are not thoroughly understood. We performed whole transcript expression profiling in 10 grade I and four grade II meningiomas, three of whic...

Journal: :Pediatrics 2015
Roger F Soll William O Tarnow-Mordi

There are many potential benefits of delayed or deferred cord clamping (DCC) compared with immediate cord clamping (ICC). Increasing placental transfusion by DCC increases neonatal blood volume and improves transitional hemodynamics. DCC may also increase iron stores, reducing childhood anemia and increasing the transfer of stem cells, which may have antiinflammatory neurotropic and neuroprotec...

Journal: :Canadian Urological Association Journal 2020

Journal: :Physics in medicine and biology 2010
H Schlattl M Zankl J Becker C Hoeschen

Automatic tube current modulation (TCM) is used in modern CT devices. This is implemented in the numerical calculation of dose conversion coefficients for CT examinations. For four models of adults, the female and male reference models of ICRP and ICRU and a lighter and a heavier female model, dose conversion coefficients normalized to CTDI(vol) (DCC(CT)) have been computed with a Monte Carlo t...

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