Corneal transplantation has evolved rapidly over the past decade, as surgeons strive to refine selective tissue transplantation to treat diseases that affect specific layers of the cornea. The first successful penetrating corneal transplantation was performed by Eduard Zirm in 1905. In 1931, Ramon Castroviejo, MD, while a fellow at Mayo Clinic, refined the techniques for penetrating keratoplast...

The concept of lamellar keratoplasty (LK) is not new. However, newer forms of lamellar keratoplasty techniques have emerged in the last decade or so revolving around the concept of targeted replacement of diseased corneal layers. These include anterior lamellar keratoplasty (ALK) techniques that aim to selectively replace diseased corneal stroma and endothelial keratoplasty techniques aiming to...

Penetrating keratoplasty (PKP) has a long track record of high success rates compared to other tissue and organ transplantations. Despite the immunologic privilege of the cornea, the issue of immunological rejection cannot be overlooked and endothelial rejection is observed in up to 20% of eyes undergoing PKP. 1 Repeat keratoplasties after rejection are increasingly more prone to rejection and ...

Case reporting the use of one donor cornea for two transplantation procedures: deep anterior lamellar keratoplasty (DALK) in a case of an imminent corneal perforation caused by herpetic stromal necrosis, and Descemet stripping with endothelial keratoplasty (DSEK) in an eye with pseudophakic bullous keratopathy (PBK). Descemet's membrane (DM), denuded by stromal necrosis, served as the starting ...

NOVEMBER/DECEMBER 2010 CATARACT & REFRACTIVE SURGERY TODAY EUROPE 23 F ull-thickness penetrating keratoplasty (PKP) has been the preferred corneal transplantation technique since the procedure was first described in 1905 by Eduard Zirm.1 Today, PKP generally results in clear corneal grafts, with a graft survival rate of up to 72% at 5 years.2 However, the procedure is frequently complicated by ...

PURPOSE To analyze the 6-month anterior and posterior topographic changes of the cornea after deep lamellar endothelial keratoplasty. METHODS Orbscan topographies of 22 eyes from 21 patients with corneal decompensation were retrospectively analyzed: 11 eyes received a 9-mm scleral access incision (large-incision group) and 11 eyes received a 5-mm scleral access incision (small-incision group)...

Objective. To evaluate the therapeutic effect of big bubble deep anterior lamellar keratoplasty (DALK) in patients with deep fungal keratitis. Methods.Consecutive patients who had DALK for deep fungal keratitis at Shandong Eye Hospital between July 2011 and December 2012 were included. In all patients, the infiltration depth was more than 4/5ths of the corneal thickness. DALK surgery was perfor...