Copyright © 2013 Massachusetts Medical Society. The risk of venous thromboembolism is four to seven times as high among patients with cancer as among persons without this disease.1,2 This risk is highest for patients with certain types of solid tumors and hematologic cancers and is increased for patients who are receiving chemotherapy or radiotherapy, who have undergone operative procedures, wh...

OBJECTIVE To determine how length of anticoagulation and clinical presentation of venous thromboembolism influence the risk of recurrence after anticoagulant treatment is stopped and to identify the shortest length of anticoagulation that reduces the risk of recurrence to its lowest level. DESIGN Pooled analysis of individual participants' data from seven randomised trials. SETTING Outpatie...

OBJECTIVE To examine the duration and magnitude of increased risk of venous thromboembolism after different types of surgery. DESIGN Prospective cohort study (Million Women Study). SETTING Questionnaire data from the Million Women Study linked with hospital admission and death records. PARTICIPANTS 947 454 middle aged women in the United Kingdom recruited in 1996-2001 and followed by reco...

BACKGROUND AND OBJECTIVE Venous thromboembolism includes two closely related clinical manifestations: deep vein thrombosis (DVT), more commonly of the lower limbs, and pulmonary embolism. Pulmonary embolism is the most common cause of preventable death in hospitalized patients. The definition of the risk factors for venous thromboembolism should allow to adopt the most suitable prophylactic reg...

Immune thrombocytopenic purpura and venous thromboembolism are rare but known complications of ulcerative colitis. Although several case studies have examined the treatment options available for ulcerative colitis patients presenting with immune thrombocytopenic purpura, there have been no reported cases that describe the optimal treatment for patients with ulcerative colitis and immune thrombo...

BACKGROUND The clinical course of cerebral sinus-venous thrombosis (CSVT) is largely unknown because prospective studies with a long follow-up and with the goal to assess thrombosis recurrence rate and predisposing factors for recurrence are lacking. METHODS AND RESULTS One hundred forty-five patients with a first CSVT were followed up for a median of 6 years after discontinuation of anticoag...

There are various region-specific challenges to the diagnosis and effective treatment of venous thromboembolism in Latin America. Clear guidance for physicians and patient education could improve adherence to existing guidelines. This review examines available information on the burden of pulmonary embolism and deep vein thrombosis in Latin America and the regional issues surrounding the diagno...