introduction: hemodialysis patients often develop resistance to recombinant human erythropoietin due to functional iron deficiency. in these patients iron therapy can be hazardous leading to hemosiderosis. recent studies have suggested that intravenous ascorbic acid may be able to improve this hyporeponsiveness. the aim of this study was to evaluate the effect of intravenous ascorbic acid on fu...

background: pregnant women take iron supplements in order to prevent iron deficiency anemia which may have undesirable effects for both the mother and fetus. this study aimed to compare the daily and intermittent dose of iron supplementation in blood and iron indices in healthy pregnant women.methods: in this clinical trial study, 145 healthy pregnant women were selected with hbx0511g%. the par...

background: exposure to sunlight is the main source of vitamin d production. this study was performed to assess the status of serum vitamin d across the different seasons in geographic region of babol, with latitude of 36 in northern iran. methods: the study – female participants were 15 years old and above selected prospectively according to the inclusion criteria who attended an outpatient cl...

background: familial chylomicronemia syndrome is a rare disorder of lipoprotein metabolism due to familial lipoprotein lipase or apolipoprotein c-ii deficiency or the presence of inhibitors to lipoprotein lipase. it manifests as eruptive xanthomas, acute pancreatitis, and lipaemic plasma due to marked elevation of triglyceride and chylomicrons levels. case presentation: we report a rare case of...

background functional iron deficiency (fid) may cause erythropoietin resistance in patients under hemodialysis (hd). since the role of chronic inflammation or oxidative stress in its pathogenesis is unclear, controversy remains to whether intravenous iron or intravenous ascorbic acid (an antioxidant) can improve this anemia due to decreased iron availability. objectives the current study compar...

background: vitamin d (vit d) is linked to various conditions including musculoskeletal, metabolic and   cardiopulmonary diseases. however, it is not clear whether correction of vit d deficiency exerts any beneficial effect in patients with pulmonary hypertension. methods: this study was a prospective uncontrolled longitudinal study. patients with pulmonary hypertension and vit d deficiency wer...

non:union: is common complication of fracture management. various factors are involved in its occurring. metabolic and endocrine factors are often overlooked. so that aim of study was to evaluate the level of vitamin d and pth in patients with unexplained non:union: and fractures due to low energy trauma. in the case control study, 30 patients with tibial non:union: compared with 32 patients wi...

background: the iron deficiency anemia (ida) is a common cause of referral to medical departments. chronic gastrointestinal (gi) blood loss is important cause of ida and also an alarming sign of serious underlying disease. the information concerning ideal evaluation of the gastrointestinal tract in patients with the ida is scant. we designed a prospective study to determine the frequency of gi ...

background: glucose-6-phosphate dehydrogenase (g6pd) deficiency is one of the most known enzyme defects in iran with various genetic mutations. we aimed to study the predisposing factors of hemolysis in children with g6pd deficiency. methods: this study was done during 2007-2012 in two referral centers of mofid children's hospital and baqiyatallah hospital, tehran, iran. the hospital records of...

this study was undertaken to define the epidemiological aspects of thyroid carcinoma in iran, an area of endemic iodine deficiency nearly until recently. the tehran cancer institute data system registry (tcidsr) was used to identify patients with different histological types of thyroid cancer (tc) in iran. data were analyzed from 438 thyroid cancer cases identified by the tcidsr in 1998-99. dis...