BACKGROUND Pancreatic adenocarcinoma (PAC) is one of the most intractable malignancies. In order to search for potential new therapeutic targets, we relied on computational methods aimed at identifying transcription factor binding sites (TFBSs) over-represented in the promoter regions of genes differentially expressed in PAC. Though many computational methods have been implemented to accomplish...

Engineered dynamical maps combining coherent and dissipative transformations of quantum states with measurements, have demonstrated a number technological applications, promise to be crucial tool in thermodynamic processes. Here, we exploit the control on effective open spin qutrit dynamics an NV center, experimentally realize autonomous feedback process (Maxwell demon) tunable strength. The is...

A classic argument for skepticism about the external world runs as follows. First: we cannot know that the evil-demon hypothesis is false, where the evil-demon hypothesis says that all of our sensory experiences have been produced by an evil demon. Second: if we cannot know that the evil-demon hypothesis is false, we cannot know we have hands. Conclusion: We cannot know we have hands. Generaliz...

We discuss the thermodynamic aspects of a single qubit based device, powered by weak quantum measurements, and feedback controlled Maxwell's demon. both discrete time-continuous operation measurement device at finite temperature reservoir. In example where demon acquires information via we find that variables including heat exchanged, extractable work, entropy produced are completely determined...

The mechanisms by which RNA polymerase moves along DNA during elongation have been difficult to determine experimentally. In this issue of Cell, Bar-Nahum et al. (2005) show that back and forth sliding of RNA polymerase on DNA may be coupled to bending of an alpha helix, which can alternately occlude and expose the NTP binding site. Transcription factors can regulate elongation by modulating th...

Maxwell's Demon is at the heart of interrelation between quantum information processing and thermodynamics. In this thought experiment, a demon generates temperature gradient two thermal baths initially equilibrium by gaining single-particle level applying classical feed-forward operations, allowing for extraction work. Here we implement photonic version with active in fibre-based system using ...

Р. 8. Bakeyev Rinat A. Tomsk State University. THE PLOT OF M.YU. LERMONTOV’S POEM «DEMON» IN THE STRUCTURE OF F.M. DOSTOEVSKY’S NOVEL «IDIOT». In the article the communication of M.Yu. Lermontov’s poem «Demon» and F.M. Dostoevsky's novel «Idiot» at the level of characterology and plot organization is studied. In this context the analysis of five plot checkpoints of the named works of art is car...

We derive from kinetic theory, fluid mechanics and thermodynamics the minimal continuum-level equations governing the flow of a binary, non-electrolytic mixture in an isotropic porous medium with osmotic effects. For dilute mixtures, these equations are linear and in this limit provide a theoretical basis for the widely used semi-empirical relations of Kedem & Katchalsky (Kedem & Katchalsky 195...